Chronic fatigue affects an estimated 2.5 million Americans, with many more likely undiagnosed or misdiagnosed, according to the Centers for Disease Control and Prevention (CDC). This complex condition often involves multiple organ systems, including neurological, immune, and endocrine pathways. Despite its prevalence and profound impact on daily life, chronic fatigue is frequently overlooked or misattributed to stress, depression, or lifestyle factors by healthcare professionals. Persistent underdiagnosis leaves countless individuals struggling without answers or effective treatment, highlighting the urgent need to explore lesser-known causes and improve medical awareness.
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49. Underlying Neurological Disorders Early neurological disorders, such as Parkinson’s disease or the initial stages of dementia, can present with unexplained fatigue long before classic symptoms…