Health

Early Signs of Adrenal Stress

22. Hair Loss Chronic adrenal stress and hormonal imbalances can disrupt the natural hair growth cycle, leading to noticeable hair shedding or thinning. Cortisol and other… Diana Yasinskaya - August 14, 2025

According to the Mental Health Foundation and the American Institute of Stress, over 74% of UK adults and 77% of US adults reported feeling overwhelmed by stress in 2022. The adrenal glands, small organs above the kidneys, are responsible for producing essential hormones like cortisol and adrenaline that regulate stress response. However, early signs of adrenal stress often go unnoticed, making timely diagnosis and intervention a widespread challenge.

1. Persistent Fatigue

1. Persistent Fatigue
A weary individual with drooping eyelids lounges on a couch, clearly struggling to keep their energy levels up. | Generated by Google Gemini

The adrenal glands play a critical role in regulating the body’s energy levels by producing cortisol, a hormone that helps manage the sleep-wake cycle and the response to stress. When the adrenal glands are under persistent stress, their ability to produce adequate cortisol may be compromised, leading to a sensation of chronic tiredness. This type of fatigue is not simply the result of poor sleep or overexertion; instead, it persists even after a full night’s rest or a period of relaxation.

For example, someone experiencing adrenal stress may wake up feeling unrefreshed, struggle to stay alert during the day, or have difficulty concentrating despite getting enough sleep. According to the Endocrine Society, persistent fatigue that does not improve with rest can be an early indicator of adrenal dysfunction. If ongoing tiredness continues for several weeks and interferes with daily activities, it may be wise to consult a healthcare provider for further evaluation. Recognizing this subtle sign early enables better management of potential adrenal issues before they progress to more serious health concerns.

2. Difficulty Getting Up in the Morning

2. Difficulty Getting Up in the Morning
A groggy person reaches for their morning alarm as soft sunrise light filters through the bedroom window. | Generated by Google Gemini

One of the most telling early indicators of adrenal stress is difficulty getting up in the morning, even after what should be a restorative night’s sleep. Under normal conditions, the adrenal glands release a surge of cortisol in the early morning hours, signaling the body to wake up, feel alert, and start the day. This natural rhythm is crucial for maintaining energy and cognitive function throughout the day.

However, when the adrenal glands are overtaxed or beginning to falter, this morning cortisol surge may be blunted or delayed. The result can feel similar to the phenomenon known as ‘sleep inertia,’ a temporary state of grogginess and impaired performance upon waking. But while sleep inertia typically fades within 15-30 minutes, adrenal-related grogginess often lingers well into the morning, sometimes lasting for hours.

If you consistently wake up feeling foggy, unmotivated, or struggle to get moving despite adequate sleep, it may be a sign that your adrenal glands are under stress. According to research published by the National Institutes of Health, persistent morning grogginess and difficulty waking are hallmark symptoms of disrupted cortisol rhythms and should not be ignored.

3. Craving Salty Foods

3. Craving Salty Foods
A tempting bowl of crispy chips sits beside a classic salt shaker, ready for the ultimate salty snack fix. | Generated by Google Gemini

The adrenal glands play a vital role in maintaining the body’s sodium balance through the production of the hormone aldosterone. Aldosterone regulates sodium and potassium levels, helping to control blood pressure and fluid balance. When adrenal function becomes compromised, as in the early stages of adrenal stress or insufficiency, aldosterone production can drop. This decrease may cause the body to excrete more sodium, leading to a sudden craving for salty foods as a compensatory mechanism.

Many people experiencing adrenal stress report an increased desire for salty snacks such as chips, pretzels, or salted nuts. This craving is a physiological response to the body’s attempt to restore sodium levels. According to the Hormone Health Network, abrupt and strong cravings for salt can be a warning sign of underlying adrenal issues. Notably, these cravings are often new or significantly stronger than any previous preferences for salty foods.

Tracking any sudden changes in taste, especially an increased appetite for salty foods, can provide valuable clues about adrenal health. If you notice a persistent and unexplained urge to consume salty snacks, it is important to discuss this symptom with a healthcare provider for further investigation.

4. Unexplained Weight Changes

4. Unexplained Weight Changes
Cortisol imbalance disrupts metabolism, leading to unexpected weight changes and altered fat distribution.

Cortisol, produced by the adrenal glands, plays a significant role in regulating metabolism and how the body processes fats, proteins, and carbohydrates. When cortisol levels become imbalanced due to adrenal stress, this can disrupt normal metabolic function and lead to noticeable changes in body weight. Individuals may experience unexplained weight gain, particularly around the abdomen, or, conversely, unexpected weight loss, even when their eating habits and activity levels remain the same.

Research from the National Institutes of Health indicates that elevated or insufficient cortisol can alter fat storage and appetite, often resulting in persistent changes to body composition. For example, higher cortisol levels may increase cravings for high-calorie foods and promote fat accumulation, while very low cortisol can lead to loss of appetite and muscle wasting.

If you notice a gradual or sudden shift in weight or body shape that cannot be explained by changes in diet, exercise, or other lifestyle factors, it may be time to consider the impact of adrenal health. Persistent, unexplained weight changes—especially when coupled with other symptoms—warrant further assessment by a medical professional.

5. Decreased Stress Tolerance

5. Decreased Stress Tolerance
A frustrated person buries their face in their hands, visibly overwhelmed by a wave of stress and emotion. | Generated by Google Gemini

The adrenal glands are central to the body’s fight-or-flight response, producing hormones like cortisol and adrenaline that help manage both physical and emotional stress. When the adrenals are under chronic strain, their ability to modulate stress responses can become impaired, making even minor challenges feel overwhelming. This decreased stress tolerance often manifests as emotional reactivity, irritability, or anxiety in situations that previously felt manageable.

For instance, a person under adrenal stress may find themselves snapping at loved ones over trivial issues, becoming uncharacteristically tearful, or feeling paralyzed by decisions that once seemed routine. According to the National Institutes of Health, diminished stress resilience is a hallmark of adrenal dysfunction and can interfere with personal and professional relationships.

If you observe a pattern of overreacting to everyday stressors, or if your ability to cope with pressure has noticeably declined, it may be a sign that your adrenal glands are struggling. Persistent emotional outbursts or ongoing feelings of being overwhelmed—especially when combined with other symptoms—should prompt a discussion with a healthcare provider to explore possible adrenal involvement and obtain appropriate support.

6. Frequent Illness or Infections

6. Frequent Illness or Infections
A person bundled in blankets clutches a box of tissues, with a thermometer resting nearby on the table. | Generated by Google Gemini

Cortisol, one of the major hormones produced by the adrenal glands, has a crucial role in regulating the immune system. While healthy levels of cortisol help control inflammation and allow the immune system to respond appropriately to threats, chronically low or dysregulated cortisol can lead to immune suppression. This makes the body more vulnerable to common illnesses, such as colds, flu, and other minor infections.

Individuals experiencing adrenal stress may notice that they are becoming sick more often or that it takes longer to recover from common ailments. For example, someone might catch every cold that circulates at work or find that a mild infection lingers for weeks. The National Institutes of Health points out that disruptions in cortisol production can impair immune cell function and increase susceptibility to infections.

If you observe a pattern of frequent or prolonged illnesses that cannot be explained by other health conditions or environmental factors, it may indicate underlying adrenal dysfunction. Keeping track of how often you become sick and how long it takes to recover can provide valuable information for healthcare providers assessing potential adrenal stress.

7. Brain Fog

7. Brain Fog
A puzzled individual stands with a thought bubble overhead, revealing a colorful illustration of a tangled brain. | Generated by Google Gemini

Brain fog is a common yet often overlooked symptom associated with adrenal fatigue and stress. When adrenal gland function is compromised, the resulting imbalance in cortisol and other hormones can negatively impact brain chemistry and cognitive processes. This may lead to persistent mental cloudiness, forgetfulness, and difficulty concentrating on everyday tasks.

For many people, brain fog becomes apparent in work or school settings, where sustained attention and memory are crucial. Simple activities, such as following instructions, making decisions, or recalling important information, can suddenly feel overwhelming. According to the Psychology Today, hormonal disruptions—including those caused by adrenal stress—are a recognized cause of cognitive impairment and reduced mental clarity.

If you consistently struggle with focus, experience lapses in memory, or find it hard to process information despite getting sufficient rest, it may be a sign of underlying adrenal issues. Tracking how often you feel mentally foggy and how it affects your daily functioning can help you and your healthcare provider identify patterns and potential causes. Persistent brain fog should not be ignored, as it can impact productivity, learning, and overall quality of life.

8. Lightheadedness When Standing

8. Lightheadedness When Standing
Adrenal glands regulate blood pressure via aldosterone; dysfunction can cause orthostatic dizziness on standing.

The adrenal glands are essential for maintaining proper blood pressure, particularly through the secretion of aldosterone, which helps regulate sodium and fluid balance. When adrenal function is compromised, the body may struggle to retain enough sodium and maintain stable blood pressure—especially during rapid changes in posture. As a result, individuals with adrenal stress may experience a sensation of lightheadedness or dizziness when standing up quickly, a phenomenon known as orthostatic hypotension.

This can feel similar to the brief dizziness most people occasionally experience after getting up too fast, but with adrenal stress, these symptoms may occur more frequently or with greater intensity. According to the Mayo Clinic, persistent or recurring episodes of postural dizziness can indicate an underlying issue with blood pressure regulation, often linked to adrenal hormone imbalance.

If you notice recurring lightheadedness, faintness, or blurred vision when changing positions—especially if it happens daily or interferes with normal activities—it’s important to monitor these symptoms closely. Documenting how often and under what circumstances these episodes occur can aid healthcare providers in assessing potential adrenal involvement and preventing related complications.

9. Low Libido

9. Low Libido
Adrenal hormone imbalance from chronic stress may lower DHEA, disrupting libido and sexual health.

The adrenal glands contribute to the production of several hormones that are integral to sexual health, including DHEA (dehydroepiandrosterone), which is a precursor to both estrogen and testosterone. When the body is under chronic stress and adrenal function is impaired, the production of these hormones can decrease, often resulting in a noticeable reduction in sex drive. This hormonal imbalance can disrupt the body’s natural rhythms and diminish libido, even in the absence of other obvious stressors or relationship issues.

A sudden or gradual loss of interest in sexual activity, which cannot be attributed to relationship challenges, aging, or other lifestyle changes, may be a signal of underlying adrenal dysfunction. As noted by the Harvard Medical School, stress and related hormone fluctuations can significantly impact desire and sexual satisfaction in both men and women.

If you experience a notable and persistent decrease in libido, especially when accompanied by fatigue or other physical changes, it’s important to pay attention to these shifts. Tracking changes in sexual interest over time can be a helpful discussion point with a healthcare provider, who can evaluate whether adrenal health is a contributing factor.

10. Mood Swings

10. Mood Swings
Adrenal hormone imbalance impacts brain chemistry, triggering mood swings and emotional instability.

The adrenal glands produce hormones, such as cortisol and adrenaline, that have a direct influence on brain chemistry and emotional regulation. When the normal production of these hormones is disrupted by chronic stress or adrenal fatigue, mood stability can suffer. This hormonal imbalance may lead to pronounced mood swings, ranging from sudden irritability and frustration to bouts of sadness or anxiety without a clear cause.

For example, someone with adrenal stress might find themselves unexpectedly snapping at coworkers or family members one moment and feeling deeply discouraged or tearful the next. These emotional fluctuations can appear disproportionate to the situation and may be difficult to control or predict. According to the Cleveland Clinic, changes in adrenal hormone levels are a recognized factor in unexplained mood shifts and emotional sensitivity.

It is important to monitor the frequency and intensity of mood swings, especially if they arise in conjunction with physical symptoms like fatigue or sleep disturbances. Persistent emotional variability, particularly when it impacts relationships or daily functioning, should prompt consideration of adrenal health and a conversation with a healthcare professional for further evaluation.

11. Dark Circles Under Eyes

11. Dark Circles Under Eyes
A close-up of a weary face reveals pronounced dark circles and tired eyes, reflecting a restless night. | Generated by Google Gemini

Chronic adrenal stress can impact the body’s circulation and skin health, sometimes resulting in persistent dark circles under the eyes. When the adrenal glands are overworked, hormonal imbalances may cause blood vessels to dilate and become more visible beneath the thin skin around the eyes. Additionally, stress-induced changes in fluid balance and decreased skin vitality can further accentuate under-eye darkness.

In many cases, people associate dark circles with a lack of sleep. However, when these shadows persist despite adequate rest, they may be a subtle sign of underlying adrenal dysfunction. According to the Mount Sinai Health Library, while genetics and allergies can also play a role, chronic stress and fatigue often exacerbate this cosmetic concern.

If you notice that dark circles remain or worsen regardless of your sleep quality or lifestyle changes, it is worth considering their connection to hormonal and adrenal health. Keeping track of how often and under what circumstances under-eye darkness appears can be helpful in identifying patterns. Persistent, non-sleep-related dark circles should be discussed with a healthcare provider to rule out adrenal involvement or other underlying causes.

12. Increased Anxiety

12. Increased Anxiety
Adrenal hormones adrenaline and cortisol influence stress response, mood regulation, and anxiety levels.

Adrenaline and cortisol, hormones produced by the adrenal glands, are central to the body’s stress response and play a significant role in regulating mood and anxiety levels. When the adrenal glands are under chronic stress or begin to malfunction, the resulting hormonal imbalances can trigger increased feelings of nervousness, restlessness, or unease—even in the absence of any obvious external stressors.

Individuals experiencing adrenal stress may notice that they feel tense, on edge, or unable to relax, often without a clear reason. This heightened state of anxiety can be persistent or come in sudden waves, sometimes manifesting as racing thoughts, a sense of impending doom, or physical symptoms like a rapid heartbeat and shallow breathing. According to the Anxiety & Depression Association of America (ADAA), chronic stress and hormonal changes are common contributors to increased anxiety and can significantly affect daily life.

If you observe a notable rise in anxiety that does not seem to be linked to specific events or life changes, it may be worthwhile to consider the role of adrenal health. Monitoring the frequency, intensity, and triggers of anxiety can help guide discussions with a healthcare professional and support appropriate evaluation and management.

13. Poor Concentration

13. Poor Concentration
A tidy work desk bathed in soft light, with notebooks and a laptop reflecting quiet focus and deep concentration. | Generated by Google Gemini

Adrenal stress can significantly affect cognitive clarity and the ability to concentrate. The hormones produced by the adrenal glands, particularly cortisol, help regulate mental alertness and support the brain’s ability to process and retain information. When cortisol production becomes erratic or insufficient due to chronic stress, many people find it increasingly difficult to maintain focus during work, school, or even simple daily activities.

This decline in concentration often presents as a wandering or drifting mind, where it becomes challenging to stay engaged with tasks, follow conversations, or complete projects efficiently. You may notice that your thoughts frequently wander, tasks take longer than usual, or you must reread the same information repeatedly to comprehend it. According to the Psychology Today, chronic stress and hormone fluctuations are common factors that undermine attention span and mental sharpness.

If you consistently experience difficulty focusing, forgetfulness, or a lack of mental clarity that interferes with daily responsibilities, it is important to take these symptoms seriously. Persistent issues with concentration, especially when accompanied by other warning signs of adrenal stress, should be discussed with a healthcare provider to explore possible underlying causes and appropriate interventions.

14. Lowered Motivation

14. Lowered Motivation
A person slouches at a desk cluttered with crumpled goal lists, staring blankly as motivational posters hang unnoticed. | Generated by Google Gemini

Hormones produced by the adrenal glands, particularly cortisol and DHEA, play a significant role in regulating motivation and the drive to pursue daily activities. When adrenal function is compromised, these hormonal imbalances can diminish the brain’s reward system and reduce the sense of accomplishment or excitement that typically fuels productivity and engagement. As a result, individuals experiencing adrenal stress may notice a marked decline in their level of initiative and enthusiasm for tasks that once felt meaningful or enjoyable.

This lowered motivation can manifest as procrastination, avoidance of responsibilities, or a general sense of apathy about personal and professional goals. Even simple chores or hobbies may seem overwhelming or uninteresting. According to the National Institutes of Health, chronic hormonal stress can impair the neural pathways that regulate reward, leading to ongoing feelings of indifference or lack of drive.

If a loss of motivation persists over several weeks or begins to interfere with your work, relationships, or quality of life, it is important to take note. Ongoing apathy or lack of enthusiasm—especially when accompanied by other physical or emotional symptoms—should prompt a conversation with a healthcare provider to evaluate adrenal health and overall well-being.

15. Sugar Cravings

15. Sugar Cravings
Cortisol imbalance from stress disrupts blood sugar, triggering cravings for sweets and quick energy.

Stress hormones, especially cortisol, play a direct role in regulating blood sugar levels. When the adrenal glands are under strain, cortisol production can become irregular, leading to unstable blood sugar and sudden drops in energy. In response, the body may trigger intense cravings for sweets and simple carbohydrates as a quick source of fuel to restore balance. This can result in frequent urges to reach for candy, pastries, or sugary drinks, particularly during periods of fatigue or stress.

New or intensified sugar cravings are a common sign of adrenal stress, as the body attempts to compensate for fluctuating energy reserves. According to the National Institutes of Health, chronic stress and cortisol disruption often increase appetite for high-sugar foods, fueling a cycle of temporary relief followed by renewed cravings.

If you notice that you’re reaching for sweets more often or find yourself unable to resist sugary snacks despite efforts to eat healthily, it may be worth monitoring these changes. Tracking the frequency, timing, and intensity of sugar cravings can help identify patterns linked to stress and adrenal function, providing important clues for healthcare discussions and potential lifestyle adjustments.

16. Muscle Weakness

16. Muscle Weakness
Chronic cortisol imbalance leads to muscle protein breakdown, reducing strength and causing persistent fatigue.

Cortisol, a hormone produced by the adrenal glands, is involved in the regulation of protein metabolism and muscle maintenance. When cortisol levels are chronically elevated or deficient due to adrenal stress, the body may begin to break down muscle protein for energy, leading to reduced muscle strength and endurance. This process, known as muscle catabolism, can contribute to a sensation of overall weakness or fatigue in the muscles, even during routine activities such as climbing stairs, carrying groceries, or performing household chores.

Individuals experiencing adrenal dysfunction may notice that their muscles tire more quickly or feel heavy and sluggish with minimal exertion. According to the National Institutes of Health, hormonal imbalances linked to stress can impair muscle repair and increase the risk of persistent weakness or soreness.

If you begin to experience muscle fatigue that is out of proportion to your activity level, or if weakness persists despite adequate rest and nutrition, it could be an early warning sign of adrenal stress. Keeping track of the frequency and severity of muscle weakness can help you and your healthcare provider determine if additional evaluation or intervention is necessary.

17. Increased Sensitivity to Noise

17. Increased Sensitivity to Noise
A person covers their ears in distress as vibrant sound waves swirl around them, illustrating the impact of loud noise. | Generated by Google Gemini

Adrenal stress can heighten the body’s sensory perception, making ordinary sounds feel overwhelmingly loud or jarring. Stress hormones such as adrenaline and cortisol prime the nervous system for the “fight-or-flight” response, which can sharpen sensory awareness in the short term. However, when these hormones are chronically elevated or imbalanced, they may lead to increased sensitivity to everyday noise, causing discomfort or even anxiety in environments that were previously tolerable.

People experiencing adrenal dysfunction often report feeling startled or irritated by routine sounds, such as traffic, office chatter, or household appliances. According to the National Institutes of Health, sustained stress hormone exposure can lower the threshold for sensory stimuli, making the brain more reactive to noise and other environmental cues.

If you notice that you are newly bothered by sounds that never used to affect you, or if you find yourself avoiding certain places due to noise, this could be an early sign of adrenal stress. Documenting when and where these sensitivities occur, as well as their intensity, can help you and your healthcare provider identify patterns and potential underlying hormonal imbalances.

18. Digestive Issues

18. Digestive Issues
A person clutches their abdomen in discomfort, illustrating stomach pain and nausea linked to digestive system issues. | Generated by Google Gemini

Cortisol, produced by the adrenal glands, exerts significant influence over gut motility, enzyme production, and the balance of beneficial bacteria in the digestive tract. When stress levels are high and cortisol becomes chronically imbalanced, it can disrupt normal digestive processes, leading to symptoms such as bloating, cramping, constipation, diarrhea, or general stomach discomfort. This link between adrenal stress and gut function is well documented, as stress hormones can alter the speed and efficiency at which food moves through the digestive system.

Many people notice their stomach becomes upset during periods of acute stress, but with adrenal dysfunction, these symptoms may become persistent or occur even in the absence of obvious stressors. According to the Johns Hopkins Medicine, the gut-brain-adrenal axis is a key pathway through which emotional and physical stress can affect digestion and overall gastrointestinal health.

If you experience ongoing digestive disturbances that do not resolve with dietary or lifestyle changes, it may be worth considering the role of adrenal health. Paying attention to the frequency, timing, and nature of digestive symptoms can provide valuable information for healthcare providers in diagnosing potential adrenal-related issues.

19. Allergies or Sensitivities Worsening

19. Allergies or Sensitivities Worsening
A young woman sneezes uncontrollably in a blooming field, overwhelmed by an allergic reaction to airborne pollen. | Generated by Google Gemini

The adrenal glands are integral to immune system regulation through their production of cortisol, which helps control inflammation and allergic responses. When adrenal function is compromised by chronic stress, cortisol levels may fall out of balance, diminishing the body’s natural ability to moderate immune reactions. This can lead to a resurgence or intensification of allergies or sensitivities that were previously mild or dormant.

For some individuals, this manifests as frequent flare-ups of old allergies, increased sensitivity to environmental factors such as dust, pollen, or pet dander, or new food intolerances. According to the National Institutes of Health, stress-related hormonal changes can amplify histamine release and lower the threshold for allergic reactions, resulting in more pronounced symptoms like sneezing, itching, rashes, or respiratory discomfort.

If you notice that your allergic responses have become more frequent or severe, or if you develop new sensitivities without an obvious trigger, it may be related to adrenal stress. Monitoring the onset, duration, and severity of allergy symptoms can provide useful insights for healthcare providers when assessing potential adrenal involvement and guiding further diagnostic or therapeutic steps.

20. Insomnia or Disturbed Sleep

20. Insomnia or Disturbed Sleep
A glowing clock reads 2 a.m. beside tangled sheets, capturing the restless struggle of another sleepless night. | Generated by Google Gemini

Cortisol, a hormone regulated by the adrenal glands, follows a daily rhythm that helps control both falling asleep and waking. Under healthy circumstances, cortisol levels peak in the early morning and gradually decline throughout the day, reaching their lowest point at night to support restful sleep. However, chronic stress or adrenal dysfunction can disrupt this pattern, causing cortisol to spike at night and contribute to insomnia or restless sleep.

People with adrenal stress often report difficulty falling asleep, frequent awakenings in the middle of the night, or waking up too early and being unable to return to sleep. This feedback loop between cortisol and sleep can exacerbate fatigue, further taxing the adrenal glands. The Sleep Foundation explains that hormonal imbalances, especially those involving stress hormones, are a common underlying factor in sleep disturbances.

If you experience ongoing trouble sleeping, whether it’s difficulty drifting off, staying asleep, or waking unrefreshed, it’s important to track these patterns. Persistent or worsening sleep issues, particularly when accompanied by other symptoms of adrenal stress, should prompt a discussion with a healthcare provider for targeted evaluation and intervention.

21. Headaches

21. Headaches
Adrenal stress disrupts hormone balance, increasing risk of tension headaches and stress-related migraines.

Hormonal fluctuations resulting from adrenal stress can contribute to frequent tension headaches and even migraines. Cortisol and other adrenal hormones help regulate blood vessel tone, inflammation, and the body’s perception of pain. When these hormones are imbalanced due to chronic stress, the likelihood of developing headaches increases. Tension headaches often present as a dull, persistent ache around the temples, forehead, or back of the head, while stress-induced migraines may involve throbbing pain, sensitivity to light and sound, and even nausea.

Individuals under ongoing adrenal strain may notice that headaches occur more frequently or with greater intensity than usual. For example, a person might start experiencing headaches several times a week, especially during periods of heightened stress or fatigue. The American Migraine Foundation highlights that chronic stress is a well-established trigger for both tension-type headaches and migraines.

If you find that headaches have become a regular occurrence—particularly if they coincide with other symptoms such as fatigue, sleep disturbances, or mood changes—it is important to consider adrenal health as a potential underlying factor. Persistent or worsening headaches should be discussed with a healthcare provider for comprehensive evaluation.

22. Hair Loss

22. Hair Loss
Chronic adrenal stress triggers hormonal imbalances, accelerating hair follicle shedding and noticeable thinning.

Chronic adrenal stress and hormonal imbalances can disrupt the natural hair growth cycle, leading to noticeable hair shedding or thinning. Cortisol and other adrenal hormones influence the function of hair follicles, and when the body is under prolonged stress, more hair follicles may shift prematurely from the growth phase (anagen) into the resting or shedding phase (telogen). This phenomenon, known as telogen effluvium, results in increased hair loss, which is often most apparent when brushing or washing the hair.

Individuals experiencing adrenal dysfunction may observe more strands left behind on pillows, in hairbrushes, or clogging shower drains. As reported by the American Academy of Dermatology Association, stress is a common but often overlooked trigger for sudden or excessive hair shedding.

If you notice a significant increase in hair loss or visible thinning—especially when it occurs alongside other symptoms of adrenal stress, such as fatigue or changes in weight—it is important to monitor these changes and discuss them with a healthcare provider. Early intervention can help identify the underlying cause and guide appropriate treatment, potentially reducing long-term impacts on hair health.

23. Dry Skin

23. Dry Skin
A close-up of a woman gently applying moisturizer to her flaky, dry skin, highlighting the importance of hydration. | Generated by Google Gemini

Hormonal imbalances resulting from adrenal stress can significantly affect the skin’s ability to retain moisture. Cortisol and other adrenal hormones help regulate fluid balance, oil production, and skin barrier function. When these hormones are out of sync due to chronic stress or adrenal fatigue, the skin may become noticeably dry, rough, or flaky—even in individuals who previously had well-hydrated skin.

This sudden or persistent dryness may not respond to typical moisturizers and can be seen on the hands, face, or other areas of the body. According to the Harvard Health Publishing, stress and hormonal disruptions are common causes of ongoing skin dehydration and irritation.

If you notice that your skin remains dry, itchy, or rough despite maintaining your usual skincare routine and hydration habits, it may be worth considering adrenal health as a factor. Persistent dry skin, especially when it develops alongside other symptoms like fatigue or hair loss, should be documented and discussed with a healthcare provider. Early recognition of these changes can help identify underlying hormonal imbalances and guide appropriate treatment to restore skin health and comfort.

24. Joint Pain or Stiffness

24. Joint Pain or Stiffness
An elderly person gently massages their swollen, stiff hands, visibly struggling with the discomfort of arthritis and joint pain. | Generated by Google Gemini

The adrenal glands help control the body’s inflammatory response by producing cortisol, a hormone with powerful anti-inflammatory effects. When adrenal function is compromised and cortisol levels are either too low or irregular, inflammation can increase, potentially resulting in joint pain, swelling, or stiffness. This is especially true in the morning or after periods of inactivity, as the body’s inability to manage inflammation can make joints feel achy or slow to loosen up.

For example, someone under adrenal stress may wake up with stiff hands and knees or notice that their joints are more tender and less flexible than usual. These symptoms can arise unexpectedly and may not be related to overuse or injury. According to the Arthritis Foundation, chronic stress and hormonal imbalances are known to exacerbate inflammation and contribute to musculoskeletal discomfort.

If you develop new or worsening joint pain, stiffness, or swelling—particularly if it is persistent and not explained by recent activity—it is important to take note. Monitoring these symptoms, especially when they occur alongside other signs of adrenal stress, can help guide timely assessment and intervention with your healthcare provider.

25. Menstrual Irregularities

25. Menstrual Irregularities
A hand marks important dates on a calendar with red circles, highlighting awareness of the menstrual cycle and women’s health. | Generated by Google Gemini

Chronic stress and adrenal dysfunction can disrupt the delicate balance of hormones that regulate the menstrual cycle. The adrenal glands influence levels of cortisol and DHEA, which interact with other reproductive hormones such as estrogen and progesterone. When stress hormones are persistently elevated or imbalanced, they can interfere with the normal signaling of the hypothalamic-pituitary-gonadal axis, potentially leading to missed, delayed, or irregular periods.

Women experiencing adrenal stress may notice changes such as skipped cycles, heavier or lighter bleeding, increased premenstrual symptoms, or unpredictable timing of menstruation. These alterations can occur even in those who previously had regular cycles. The American College of Obstetricians and Gynecologists (ACOG) highlights that physical and emotional stress are among the most common causes of menstrual irregularities.

If you observe unusual changes in your menstrual pattern, it’s important to track the timing, duration, and nature of these alterations. Persistent or significant irregularities—especially in combination with other symptoms of adrenal stress—should be discussed with a healthcare provider. Comprehensive tracking can help identify hormonal imbalances and support appropriate evaluation and treatment strategies.

26. Low Blood Pressure

26. Low Blood Pressure
A nurse checks a patient’s blood pressure with a cuff as the patient appears lightheaded and close to fainting. | Generated by Google Gemini

Aldosterone, a hormone produced by the adrenal glands, plays a critical role in regulating blood pressure by controlling sodium and water balance in the body. When adrenal function is compromised, aldosterone production may decrease, leading to lower blood volume and, consequently, low blood pressure (hypotension). This can result in symptoms such as feeling faint, dizzy, or weak, particularly when standing up quickly or after extended periods of sitting or lying down.

Some individuals with adrenal stress may find themselves experiencing episodes of lightheadedness, blurred vision, or even near-fainting in situations that previously did not cause any problems. According to the Mayo Clinic, persistent low blood pressure can be a sign of underlying hormonal imbalance, especially when associated with adrenal insufficiency.

If you notice these symptoms, it’s important to check your blood pressure regularly and document any significant changes or recurrent episodes of dizziness and faintness. Persistent or unexplained low blood pressure—particularly when combined with other warning signs of adrenal stress—should prompt a discussion with your healthcare provider for further evaluation and appropriate management.

27. Sensitivity to Cold

27. Sensitivity to Cold
Wrapped tightly in a cozy blanket, a person shivers from cold sensitivity, seeking warmth and comfort indoors. | Generated by Google Gemini

The adrenal glands, through their production of hormones such as cortisol, play a role in regulating the body’s metabolism and temperature. When adrenal function is impaired due to chronic stress or fatigue, the body’s ability to generate and maintain warmth can diminish. This often results in increased sensitivity to cold, where individuals may feel chilly or develop goosebumps in environments that never bothered them before, even when others around them are comfortable.

Common examples include needing extra layers or blankets, experiencing cold hands and feet, or feeling an overall sense of chilliness, especially during periods of fatigue or after minimal exposure to cooler temperatures. According to the Johns Hopkins Medicine, hormonal imbalances—including those resulting from adrenal dysfunction—can interfere with the body’s internal thermostat and lead to cold intolerance.

If you notice that you are feeling cold more frequently or intensely than usual, it may be a subtle sign of adrenal stress. Keeping track of when and how often these sensations occur can help your healthcare provider identify patterns, rule out other causes, and determine whether adrenal function should be further evaluated.

28. Slow Recovery from Illness

28. Slow Recovery from Illness
Adrenal glands regulate immune response and healing by balancing cortisol and inflammation during illness.

The adrenal glands play a vital role in modulating the immune response and supporting the body’s ability to heal and recover from illness. Cortisol, in particular, helps regulate inflammation and ensures that the immune system responds appropriately to infections and injuries. When adrenal function is compromised due to chronic stress or fatigue, the healing process can slow down, leaving individuals more susceptible to lingering or recurrent illnesses.

For example, a common cold or mild respiratory infection that would typically resolve within a week may persist for several weeks, or symptoms may seem to improve only to return again. According to the National Institutes of Health, inadequate cortisol production can impair immune cell activity and slow tissue repair, increasing the risk of complications and secondary infections.

If you notice that your body takes longer than usual to bounce back from everyday illnesses, or that you frequently relapse after appearing to recover, it may signal underlying adrenal stress. Seeking timely medical attention and sharing these patterns with your healthcare provider can help uncover hormonal imbalances and guide effective management to restore optimal immune resilience.

29. Increased PMS Symptoms

29. Increased PMS Symptoms
A young woman sits on her bed, holding a heating pad, her expression reflecting the ups and downs of PMS mood swings. | Generated by Google Gemini

The adrenal glands influence the production of several hormones that interact with the female reproductive system, including cortisol and DHEA. Chronic adrenal stress disrupts the delicate balance between these hormones and sex hormones like estrogen and progesterone, which can intensify premenstrual syndrome (PMS) symptoms. Women under adrenal strain may experience more severe mood swings, irritability, bloating, breast tenderness, headaches, or fatigue in the days leading up to menstruation.

For example, PMS symptoms that were once mild may suddenly become debilitating, interfering with work, relationships, or daily routines. According to the National Institutes of Health, chronic stress and resulting hormonal imbalances are significant contributors to both the frequency and intensity of PMS complaints.

If you observe that your premenstrual symptoms have worsened or changed in character—such as increased pain, mood disturbances, or extended duration—it’s important to track these shifts over time. Recording the severity and type of symptoms each cycle can provide valuable insights for your healthcare provider. Persistent or escalating PMS symptoms, especially when accompanied by other signs of adrenal stress, may warrant a closer look at your hormonal health.

30. Poor Wound Healing

30. Poor Wound Healing
Cortisol regulates inflammation and healing; imbalances may slow wound recovery and tissue repair.

Cortisol, produced by the adrenal glands, is crucial for orchestrating the body’s healing and tissue repair processes. It helps control inflammation and modulate the immune response at the site of injury. When cortisol levels are chronically imbalanced due to adrenal stress or fatigue, the body’s ability to heal wounds efficiently may be compromised. This can lead to small cuts, scrapes, or bruises taking noticeably longer to close, scab, or fade compared to what is typical for you.

For instance, you might notice that minor injuries persist for weeks, remain red or swollen, or are more prone to infection. According to the National Institutes of Health, stress-induced hormonal disruption can reduce the effectiveness of the immune system and delay tissue regeneration, increasing the risk of complications from even trivial wounds.

If you observe slow or incomplete wound healing—especially in the absence of other risk factors such as diabetes or vascular disease—it may be an early indicator of adrenal dysfunction. Paying attention to how long it takes for minor injuries to heal can help prompt timely medical evaluation and support appropriate interventions to restore healthy adrenal and immune function.

31. Decreased Muscle Mass

31. Decreased Muscle Mass
A fit individual lifts weights in a bright gym, showcasing defined muscle mass and balanced body composition through exercise. | Generated by Google Gemini

Prolonged elevation of cortisol, a key hormone produced by the adrenal glands, can lead to increased protein breakdown in muscle tissue—a process known as catabolism. This hormonal imbalance diverts amino acids from muscles to supply energy during periods of chronic stress, resulting in gradual muscle loss even when regular exercise or strength training is maintained. Over time, individuals may notice a decrease in muscle tone, strength, or overall body composition despite consistent efforts to remain active.

For example, you might experience a reduction in the size or firmness of muscles, find it harder to build or maintain muscle, or observe a loss of definition in areas like the arms, legs, or abdomen. According to the National Institutes of Health, persistent high cortisol is a well-documented cause of muscle wasting and weakness, particularly in the context of chronic stress and adrenal dysfunction.

If you notice unexpected changes in muscle mass or an inability to gain muscle despite adequate nutrition and training, it is important to consider hormonal health as a contributing factor. Monitoring and discussing these changes with a healthcare provider can help uncover underlying adrenal issues and guide appropriate strategies for recovery and muscle preservation.

32. Increased Thirst

32. Increased Thirst
A thirsty person eagerly reaches for a clear glass of water, ready to quench their thirst and stay hydrated. | Generated by Google Gemini

The adrenal glands, through the secretion of hormones like aldosterone, are essential in maintaining the body’s electrolyte and fluid balance. When adrenal function is impaired, aldosterone levels can drop, leading to increased sodium loss and changes in blood volume. This shift can trigger a persistent sensation of thirst as the body attempts to restore proper hydration and sodium levels. Individuals may find themselves feeling parched or needing to drink water more frequently, even without increased physical activity or exposure to heat.

This unexplained thirst is often not relieved by typical water intake and may be accompanied by other symptoms such as dry mouth, dizziness, or frequent urination. According to the Hormone Health Network, electrolyte imbalances caused by adrenal insufficiency can prompt the body to crave fluids in an effort to maintain homeostasis.

If you observe a notable and persistent increase in thirst that cannot be explained by external factors, it may be a subtle sign of adrenal stress or dysfunction. Tracking your fluid intake and the intensity of your thirst can provide valuable information for your healthcare provider during evaluation and help identify underlying hormonal or electrolyte disturbances.

33. Palpitations or Irregular Heartbeat

33. Palpitations or Irregular Heartbeat
A close-up view of an EKG monitor displays irregular heartbeats, capturing the intensity of sudden palpitations. | Generated by Google Gemini

Adrenal hormones such as adrenaline (epinephrine) and cortisol have a direct effect on cardiovascular function, including heart rate and rhythm. When the adrenal glands are under stress or not functioning properly, these hormones can become imbalanced, leading to episodes of palpitations or an irregular heartbeat. Individuals may experience sensations of their heart racing, fluttering, or pounding unexpectedly, even while at rest or during mild activity.

For example, you might suddenly feel your heart beating rapidly or notice skipped beats that are not related to exercise, caffeine, or anxiety. These symptoms may last only a few seconds or persist for longer periods. According to the Cleveland Clinic, hormonal fluctuations—particularly those involving stress hormones—can be significant triggers for palpitations and arrhythmias.

If you experience frequent or severe palpitations, irregular heartbeats, or associated symptoms such as chest pain, dizziness, or shortness of breath, it is important to seek medical evaluation promptly. While occasional palpitations can be benign, persistent or worsening episodes—especially when accompanied by other signs of adrenal stress—may indicate an underlying hormonal or cardiovascular issue that requires professional attention.

34. Shakiness or Tremors

34. Shakiness or Tremors
A close-up of hands trembling slightly, highlighting the visible effects of a nervous system disorder. | Generated by Google Gemini

Adrenal hormones, particularly adrenaline and cortisol, influence the body’s nervous system and play a key role in the “fight-or-flight” response. When the adrenal glands are under chronic stress or dysregulated, the nervous system can become hypersensitive, resulting in physical symptoms such as shakiness or hand tremors. These involuntary movements or vibrations are often most noticeable during moments of stress, anxiety, or after sudden changes in posture or blood sugar.

For example, you may notice your hands trembling slightly when feeling anxious, fatigued, or even at rest—despite no recent caffeine intake or physical exertion. According to the Cleveland Clinic, stress-induced hormonal fluctuations are a recognized cause of temporary tremors and shaking, particularly when the body’s stress response is overactive or poorly regulated.

If you experience new or worsening shakiness, tremors, or episodes of feeling jittery—especially if these symptoms arise without obvious cause—it’s important to track their frequency and context. Persistent or unexplained tremors should be discussed with a healthcare provider, as they may be an early sign of adrenal dysfunction or another underlying health condition requiring evaluation.

35. Swelling in Ankles or Legs

35. Swelling in Ankles or Legs
A close-up view of legs resting on a bed, showing noticeable swelling and puffiness around the ankles due to edema. | Generated by Google Gemini

Aldosterone, a hormone produced by the adrenal glands, is crucial in regulating sodium and water balance within the body. When adrenal function is compromised and aldosterone levels drop, the kidneys may struggle to maintain fluid equilibrium, leading to the retention of water and sodium in tissues. This imbalance can manifest as swelling—also known as edema—in the ankles, feet, or lower legs.

For example, you may notice your socks leaving deep indentations at the end of the day or observe puffiness around your ankles that was not present before. The swelling may worsen after long periods of standing or sitting and can sometimes be accompanied by a feeling of heaviness or tightness in the affected area. According to the Mount Sinai Health Library, persistent or unexplained swelling in the lower extremities should prompt further evaluation, as it can be a sign of hormonal or circulatory issues.

If you develop persistent or recurrent swelling in your legs or ankles—especially when it is not related to injury or a change in activity—documenting its onset, duration, and severity can help your healthcare provider assess for possible adrenal involvement and guide appropriate treatment.

36. Loss of Appetite

36. Loss of Appetite
Elevated stress hormones suppress appetite and digestion, often leading to unintended meal skipping.

Stress hormones produced by the adrenal glands, particularly cortisol and adrenaline, can have a direct suppressive effect on hunger and digestive processes. During periods of adrenal stress or dysfunction, these hormones may remain elevated or fluctuate unpredictably, leading to reduced sensations of hunger and a decreased interest in food. This can result in unintentionally skipping meals or eating far less than usual, even when the body requires nourishment.

For instance, individuals may realize they have gone most of the day without eating or may experience a general lack of enthusiasm for food, finding it difficult to finish regular portions. According to the National Institutes of Health, chronic stress and hormonal imbalances are recognized contributors to appetite loss, as the body’s fight-or-flight response shifts resources away from digestion to address perceived threats.

If you notice a persistent decrease in appetite or begin to lose weight unintentionally, it is important to monitor these changes and consider the broader context of your health. Ongoing appetite suppression—especially when coupled with other symptoms of adrenal stress—should be discussed with a healthcare provider to ensure timely evaluation and support.

37. Increased Sweating

37. Increased Sweating
Adrenaline surges from adrenal stress trigger excessive, unpredictable sweating and disrupt normal perspiration patterns…

Adrenaline, one of the primary hormones released by the adrenal glands during times of stress, directly stimulates the sweat glands and increases perspiration. Under chronic adrenal stress or dysfunction, adrenaline surges can occur more frequently or unpredictably, leading to episodes of excessive sweating without an obvious trigger. This can manifest as clammy hands, sudden sweating during mild exertion, or even night sweats that disrupt sleep.

Individuals may notice they are sweating more than usual during routine activities, or that they wake up drenched despite normal room temperatures. According to the Sleep Foundation, hormonal imbalances—especially those involving stress hormones like adrenaline and cortisol—are a well-documented cause of increased or abnormal sweating patterns, including night sweats.

If you experience frequent or unexplained episodes of sweating, particularly if they are accompanied by other symptoms such as palpitations or anxiety, it is important to track the timing and circumstances. Persistent or bothersome sweating that cannot be explained by temperature, activity, or illness should be discussed with a healthcare provider, as it may be an early marker of adrenal stress or another underlying health concern.

38. Reduced Exercise Tolerance

38. Reduced Exercise Tolerance
Adrenal glands regulate energy, blood sugar, and recovery, crucial for sustaining physical activity and stamina.

The adrenal glands are instrumental in supplying the body with the energy and stamina needed for physical activity. Cortisol and other adrenal hormones help regulate blood sugar, muscle recovery, and the body’s response to physical stress. When adrenal function is compromised, the ability to sustain exercise or recover from workouts may decline significantly. Individuals may find themselves feeling unusually fatigued during their usual routines or requiring much longer periods to recuperate after exertion.

For example, someone who previously completed a run or gym session with ease may suddenly struggle to finish, experience excessive muscle soreness, or feel exhausted for hours or days afterward. According to the National Institutes of Health, chronic stress and hormonal imbalances can decrease exercise performance and delay recovery by impairing energy metabolism and tissue repair.

If you notice that your exercise capacity has diminished, workouts feel more difficult, or you are less motivated to be active, it is important to monitor these changes. Consistently reduced exercise tolerance—especially when not related to changes in training regimen, sleep, or nutrition—may indicate underlying adrenal stress and should be discussed with a healthcare provider.

39. Restless Legs

39. Restless Legs
A pair of feet under a rumpled blanket, caught mid-movement during a restless night of tossing and turning. | Generated by Google Gemini

Adrenal hormones, particularly cortisol and adrenaline, play a significant role in regulating the nervous system and muscle activity. When these hormones become imbalanced due to chronic stress or adrenal dysfunction, it can result in sensations of restlessness or discomfort in the legs, often described as an uncontrollable urge to move them. This is commonly known as restless legs syndrome (RLS) and is especially noticeable at night or during periods of inactivity.

Individuals experiencing adrenal stress may find themselves fidgeting, shifting positions frequently, or feeling compelled to walk around to relieve the unpleasant sensations. According to the Sleep Foundation, hormonal fluctuation and stress are recognized factors that can aggravate or trigger restless legs symptoms, which can in turn disrupt sleep and contribute to daytime fatigue.

If you develop new symptoms of leg restlessness, twitching, or discomfort that interfere with your ability to fall asleep or relax, it is important to track their onset and frequency. Persistent or worsening restless legs—especially when accompanied by other signs of adrenal stress—should be brought to the attention of a healthcare provider to determine the underlying cause and appropriate management strategies.

40. Numbness or Tingling

40. Numbness or Tingling
A close-up of a hand with highlighted nerves illustrates the sensation of numbness and tingling from disrupted nerve signals. | Generated by Google Gemini

Hormonal imbalances caused by adrenal stress can influence nerve health and sensitivity, sometimes leading to sensations of numbness or tingling in the extremities. When cortisol and other adrenal hormones fluctuate abnormally, they may affect blood flow, electrolyte balance, and the way nerves transmit signals throughout the body. This can manifest as a “pins-and-needles” feeling, most commonly in the hands, feet, fingers, or toes.

For example, you might notice tingling after sitting in one position for a short time or experience intermittent numbness that does not resolve quickly. According to the Cleveland Clinic, stress and hormonal changes can alter nerve conduction or increase nerve sensitivity, sometimes resulting in these unusual sensations even in the absence of injury or pressure on the limbs.

If you experience persistent or unexplained numbness or tingling—especially when symptoms recur or spread—it’s important to pay attention and track their frequency and duration. Ongoing issues with nerve sensitivity, particularly alongside other signs of adrenal stress, should be evaluated by a healthcare provider to rule out underlying hormonal, metabolic, or neurological conditions.

41. Eye Discomfort or Dryness

41. Eye Discomfort or Dryness
A person gently applies soothing eye drops to relieve dryness and discomfort, bringing comfort to tired, irritated eyes. | Generated by Google Gemini

Hormones produced by the adrenal glands, such as cortisol, play an important role in maintaining the health and function of mucous membranes, including those on the surface of the eyes. When adrenal hormones are imbalanced due to chronic stress or adrenal dysfunction, tear production can decrease, leading to symptoms of dry, irritated, or gritty eyes. This sensation may be particularly noticeable after prolonged screen use, in air-conditioned environments, or upon waking in the morning.

Individuals experiencing adrenal stress may find that their eyes feel persistently uncomfortable, red, or sensitive to light. According to the American Academy of Ophthalmology, hormonal fluctuations are a recognized factor in the development of dry eye syndrome, which can impair visual clarity and increase the risk of eye infections.

If you notice ongoing dryness, burning, or a foreign body sensation in your eyes, especially if these symptoms persist despite using lubricating drops or adjusting your environment, it is important to track their frequency and severity. Persistent eye discomfort—particularly when associated with other signs of adrenal stress—should be discussed with a healthcare provider for proper evaluation and management.

42. Chest Tightness

42. Chest Tightness
A young woman sits with her hand on her chest, eyes closed, struggling to breathe amid visible signs of stress. | Generated by Google Gemini

Adrenal hormones, particularly adrenaline and cortisol, have a direct influence on respiratory and cardiovascular function. During periods of adrenal stress or hormonal imbalance, the body’s natural “fight-or-flight” response can become overactive, resulting in sensations of chest tightness or pressure. These symptoms may occur even in the absence of physical exertion or obvious anxiety and often present as a constricted, heavy, or uncomfortable feeling in the chest.

For example, you might notice a vague pressure across your chest while at rest, or experience difficulty taking a deep breath, especially during stressful moments or after a surge of adrenaline. According to the Harvard Health Publishing, stress and hormonal fluctuations can sometimes mimic or exacerbate respiratory symptoms, though it’s crucial to differentiate these from cardiac or pulmonary emergencies.

If you experience frequent or persistent chest tightness—particularly if it is accompanied by other symptoms such as palpitations, shortness of breath, dizziness, or pain—it is important to seek medical evaluation promptly. Severe or sudden chest pressure should always be treated as a potential emergency, as it may indicate a more serious underlying condition requiring immediate attention.

43. Frequent Urination

43. Frequent Urination
A person stands in a tiled bathroom, relieving their full bladder at a modern white toilet. | Generated by Google Gemini

The adrenal glands, particularly through the hormone aldosterone, play a vital role in regulating the balance of fluids and electrolytes in the body. When adrenal function is compromised due to stress or insufficiency, the kidneys may excrete more sodium and water, leading to increased urine output. This adrenal-renal connection can result in frequent urination, sometimes even in the absence of increased fluid intake or other obvious causes.

For instance, you might find yourself needing to use the bathroom multiple times during the day or night, disrupting sleep and daily routines. According to the Mount Sinai Health Library, hormonal imbalances—including those related to adrenal insufficiency—are recognized contributors to changes in urinary frequency.

If you notice a sudden increase in how often you urinate, or if frequent bathroom trips persist without a clear explanation (such as high fluid intake, caffeine use, or urinary tract infections), it is important to track the timing and frequency of these episodes. Persistent or unexplained frequent urination—especially when accompanied by other signs of adrenal stress—should be discussed with a healthcare provider for further assessment.

44. Back or Flank Pain

44. Back or Flank Pain
A person holds their lower back with a pained expression, highlighting discomfort in the kidney and flank area. | Generated by Google Gemini

The adrenal glands are small, triangular organs located directly above each kidney, situated toward the back of the upper abdomen. When these glands are under chronic stress or become inflamed, it can sometimes manifest as a dull ache, soreness, or discomfort in the lower back or flank area. This pain is often subtle and may not be directly linked to physical activity, injury, or posture.

Individuals experiencing adrenal stress might notice a persistent or intermittent ache around the lower ribs, just above the waist, or along the sides of the back. This discomfort can be mistaken for muscular strain or minor kidney issues. According to the Merck Manual, pain in this region may occasionally be related to adrenal gland or kidney problems rather than musculoskeletal causes.

If you observe ongoing or unexplained aches in your lower back or flank—especially when not associated with movement or physical exertion—it is important to take note. Persistent discomfort in this area, particularly when accompanied by other early signs of adrenal stress, should be evaluated by a healthcare provider to rule out underlying adrenal or renal concerns.

45. Loss of Body Hair

45. Loss of Body Hair
A close-up view of smooth skin highlighting areas of body hair loss and visible hair follicles. | Generated by Google Gemini

The adrenal glands produce androgens—hormones that contribute to the growth and maintenance of body hair in both men and women. When adrenal function is compromised by chronic stress or hormonal imbalance, androgen production may decline, potentially leading to noticeable thinning or loss of body hair. This can manifest as reduced hair density on the arms, legs, underarms, or even the pubic region, and is often more subtle than scalp hair loss.

For example, you might observe that your arm or leg hair appears lighter, patchier, or sparser than before, or notice that less hair is present in areas that were previously well-covered. According to the Hormone Health Network, a decrease in androgen levels linked to adrenal insufficiency is a known factor in the loss of body hair, particularly in women.

If you detect a sudden or gradual thinning of body hair—especially when it occurs in conjunction with other symptoms of adrenal stress—it is important to monitor these changes and share your observations with a healthcare provider. Early recognition of these patterns can help identify underlying hormonal imbalances and prompt timely evaluation and intervention.

46. Unusual Skin Pigmentation

46. Unusual Skin Pigmentation
Distinct dark patches of skin pigmentation appear on the hands, a possible symptom linked to adrenal disease. | Generated by Google Gemini

Adrenal dysfunction, particularly in cases of Addison’s disease or severe adrenal insufficiency, can lead to changes in skin pigmentation—a condition known as hyperpigmentation. This occurs because low cortisol levels trigger the pituitary gland to produce more adrenocorticotropic hormone (ACTH), which can also stimulate melanin production in the skin. As a result, individuals may develop areas of darker pigmentation, especially in skin folds, creases, scars, elbows, knees, and on the gums or inside the mouth.

For example, you might notice that the skin in your armpits, knuckles, or the creases of your palms appears unusually dark or bronzed compared to the rest of your body. These changes are often gradual but can become more pronounced over time. According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), unexplained hyperpigmentation should always be evaluated by a healthcare provider, as it can be an early sign of significant adrenal dysfunction.

If you observe new or expanding areas of darkened skin—especially in conjunction with fatigue, weight loss, or other symptoms of adrenal stress—it’s important to seek medical attention promptly for proper diagnosis and management.

47. Poor Balance

47. Poor Balance
A young boy wobbles on a balance beam, arms outstretched as he fights to regain his coordination. | Generated by Google Gemini

Adrenal hormones such as cortisol and aldosterone have a significant influence on electrolyte balance, blood pressure regulation, and overall neuromuscular coordination. When these hormones are disrupted due to adrenal stress or dysfunction, the body’s ability to maintain stable posture and balance can be compromised. This may manifest as unsteadiness, frequent stumbling, or an increased tendency to bump into objects or lose footing during everyday activities.

For instance, you might find yourself becoming unsteady when rising from a seated position, swaying while standing still, or needing to grab support more often than usual. According to the National Institutes of Health, chronic stress and hormonal imbalances can impair neuromuscular signaling, further increasing the risk of poor balance and falls, particularly in older adults.

If you notice new or worsening issues with coordination, stumbling, or dizziness—especially if these symptoms are not explained by injury, medication, or preexisting neurological conditions—it’s important to track their frequency and circumstances. Persistent balance problems, particularly when accompanied by other signs of adrenal stress, should be discussed with a healthcare provider for further evaluation and targeted support.

48. Reduced Peripheral Vision

48. Reduced Peripheral Vision
A woman undergoes an eye exam as a specialist tests her peripheral vision to detect early signs of vision loss. | Generated by Google Gemini

Chronic adrenal dysfunction can indirectly affect the health of the optic nerve and other structures involved in vision. Hormonal imbalances, particularly those involving cortisol, can influence blood flow to the eyes and nervous system, potentially contributing to changes in peripheral vision. In rare cases, conditions related to adrenal disorders, such as pituitary tumors (which may develop as a result of disrupted hormone feedback), can physically compress the optic nerves and cause a narrowing of the visual field—commonly known as tunnel vision.

People affected by these changes may notice difficulty seeing objects out of the corners of their eyes, bumping into things more often, or a shrinking of their overall field of view. According to the American Academy of Ophthalmology, any new or progressive loss of peripheral vision warrants prompt medical evaluation, as it can be a sign of serious underlying health conditions.

If you become aware of tunnel vision, increased clumsiness, or changes in the breadth of your sight, it’s important to have your eyes checked by a healthcare provider or eye specialist. Timely assessment can help identify the root cause and prevent further vision loss or complications.

49. Changes in Voice

49. Changes in Voice
Adrenal hormone imbalance impacts vocal cord strength, hydration, and elasticity, altering voice quality.

Adrenal hormones, especially cortisol and androgens, influence many body tissues—including the muscles and mucous membranes of the vocal cords. When these hormones become imbalanced due to chronic adrenal stress or dysfunction, they can affect the hydration, strength, and elasticity of the vocal cords. This may lead to noticeable changes in voice quality, such as persistent hoarseness, weakness, or an unusually raspy or deeper tone, even in the absence of a cold or upper respiratory infection.

For example, you might wake up with a weak or croaky voice that doesn’t improve throughout the day, or you may notice that your voice cracks or tires more easily during conversation. According to the American Academy of Otolaryngology-Head and Neck Surgery, chronic hormonal imbalances are among several potential causes of ongoing hoarseness or changes in voice.

If you experience persistent alterations in your voice—especially if these changes occur without obvious irritation, infection, or vocal strain—it’s important to monitor their duration and frequency. Lasting changes in voice quality, particularly alongside other signs of adrenal stress, should be discussed with a healthcare provider for thorough evaluation and targeted treatment if needed.

50. Heightened Allergic Responses

50. Heightened Allergic Responses
Raised red hives appear on a forearm during an allergy test, highlighting a visible allergic response to allergens. | Generated by Google Gemini

Adrenal stress can disrupt the body’s delicate immune balance, lowering immune tolerance and making individuals more reactive to common allergens. Normally, adrenal hormones—especially cortisol—help regulate inflammation and suppress excessive immune responses. However, when the adrenal glands are fatigued or not functioning properly, cortisol production may decrease, causing the immune system to overreact and resulting in stronger or more frequent allergic reactions.

As a result, you may find that seasonal allergies, food sensitivities, or reactions to dust, pollen, or pet dander become more intense or harder to control. Symptoms such as sneezing, itching, hives, or respiratory discomfort might escalate, or you could develop allergies to substances that never previously bothered you. According to the National Institutes of Health, chronic stress and adrenal dysfunction can heighten allergic responses by altering immune system regulation and histamine release.

If you notice new allergies or a marked increase in the severity or frequency of existing allergic reactions, it is important to document these changes and share them with your healthcare provider. Tracking the onset and evolution of allergic symptoms can offer critical insights into underlying adrenal health and guide appropriate treatment strategies.

Conclusion

Conclusion
A doctor discusses hormone test results with a patient during a routine health checkup in a bright medical office. | Generated by Google Gemini

Recognizing the early signs of adrenal stress is crucial for maintaining long-term health and preventing more serious complications. With symptoms often subtle and easily overlooked, vigilance is essential—especially if you notice multiple signs persisting over time. Early detection allows for timely intervention, which may include lifestyle adjustments, stress management, or targeted therapy. If you experience several of these symptoms, consider consulting a healthcare provider or requesting comprehensive hormone panels to assess your adrenal function. For more about hormone testing and adrenal health, visit the Endocrine Society. Taking proactive steps can help you restore balance, improve well-being, and reduce the risk of chronic health issues linked to adrenal dysfunction.

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