Silent Signs of Kidney Failure Doctors Often Miss

1. Persistent Fatigue

One of the earliest and most overlooked indicators of kidney dysfunction is persistent fatigue. When the kidneys are not filtering waste products and extra fluid from the blood efficiently, toxins begin to accumulate in the body. This toxic buildup can result in a constant feeling of tiredness or exhaustion, even after a full night’s sleep. Unlike fatigue that stems from stress, overexertion, or lack of sleep, kidney-related fatigue often persists regardless of lifestyle adjustments or rest.

Many patients may attribute ongoing tiredness to aging, busy schedules, or other chronic conditions, causing this symptom to go unrecognized. However, if you notice a decline in your energy levels that doesn’t improve with rest, or if daily activities become increasingly difficult, it’s crucial to track these changes. Keeping a fatigue diary and discussing patterns with your healthcare provider can help distinguish kidney-related exhaustion from other common causes. According to the National Kidney Foundation, unexplained fatigue is a key sign of kidney disease that should not be ignored. Early detection and intervention may improve outcomes and preserve kidney function.

2. Swelling in Ankles and Feet

Swelling in the ankles and feet, medically known as peripheral edema, is a common but often unnoticed sign of kidney dysfunction. Healthy kidneys regulate fluid balance by filtering excess water and sodium from the blood. When this process is disrupted, extra fluid accumulates in the body’s tissues, particularly in the lower extremities. This swelling may be mild at first, but can become more pronounced over time and is often more noticeable at the end of the day or after prolonged periods of sitting or standing.

While swelling can also be caused by heart failure, liver disease, or venous insufficiency, kidney-related edema typically occurs without shortness of breath or chest discomfort. In contrast, swelling from heart failure is often accompanied by these symptoms and may worsen when lying down. If you observe persistent or unexplained swelling, especially if it is associated with changes in urination or other symptoms, it’s important to consult a healthcare provider. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) recommends seeking medical advice to determine the underlying cause and to prevent further complications. Early evaluation can be crucial for protecting kidney health.

3. Changes in Urination Patterns

Alterations in urination habits can be a subtle yet telling sign of kidney dysfunction. The kidneys are responsible for filtering waste and excess fluids, which are then excreted as urine. When kidney function declines, you may notice changes such as increased frequency, particularly at night (nocturia), or, conversely, a decrease in urine output. The appearance of urine may also shift, becoming foamy or bubbly due to excess protein, or appearing darker, lighter, or tinged with blood.

These changes are often gradual and may be mistaken for minor fluctuations related to hydration, age, or bladder health. However, persistent differences—such as needing to urinate more or less often, difficulty urinating, or the presence of blood or unusual foam—should not be ignored. The National Kidney Foundation emphasizes the importance of monitoring urination patterns, as early detection of abnormalities can significantly impact outcomes. Keeping a simple log of urination frequency, volume, and any noticeable changes in appearance can be helpful when discussing symptoms with your healthcare provider. Early recognition and intervention may help slow the progression of kidney disease.

4. Trouble Concentrating

Difficulty concentrating or experiencing frequent “brain fog” can be an early, overlooked indicator of kidney problems. When the kidneys are impaired, waste products and toxins begin to accumulate in the bloodstream. These substances can negatively affect brain function, leading to issues with memory, focus, and mental clarity. The resulting cognitive impairment may be subtle, such as forgetting appointments or struggling to follow conversations, and can easily be mistaken for stress, aging, or sleep deprivation.

Unlike cognitive problems caused by neurological disorders, such as dementia, the confusion and lack of concentration linked to kidney dysfunction often occur alongside other symptoms, such as fatigue or changes in urination. If you notice persistent difficulties with memory or attention that do not improve with rest or lifestyle changes, it may be time to consider possible medical causes. The National Kidney Foundation recommends tracking episodes of brain fog, noting their duration and frequency, and discussing these patterns with your doctor. Simple strategies, such as keeping a daily journal or using memory aids, can help you monitor your mental clarity and provide valuable information for your healthcare provider during assessment.

5. Persistent Itching

Unexplained, persistent itching—also known as pruritus—can be a subtle but significant sign of underlying kidney dysfunction. When the kidneys are no longer able to effectively remove waste products and excess minerals from the bloodstream, substances such as urea and phosphorus can build up in the body. This accumulation irritates nerve endings in the skin, leading to ongoing or widespread itching that is often resistant to over-the-counter treatments and moisturizers.

Unlike itching caused by allergies, insect bites, or dermatological conditions like eczema or psoriasis, kidney-related pruritus often lacks an obvious rash or visible irritation. The sensation may be more generalized, affecting large areas such as the back, arms, or legs, and tends to persist despite self-care measures. If you experience ongoing itchiness without a clear trigger or notice it in conjunction with other symptoms like fatigue or swelling, it is important to seek medical advice. The National Kidney Foundation advises that persistent itching, especially when unexplained, should prompt further investigation to rule out kidney disease or other systemic conditions. Early consultation with a healthcare provider can lead to timely diagnosis and appropriate management.

6. Muscle Cramps

Frequent or severe muscle cramps can be an early indicator of kidney dysfunction, often overlooked as a sign of dehydration or overexertion. When the kidneys are failing, they lose the ability to properly regulate electrolyte levels, including calcium, potassium, and sodium. This imbalance can disrupt normal muscle function, leading to sudden, painful cramps that may occur in the legs, feet, or hands. Unlike the occasional cramps from physical activity or poor hydration, those associated with kidney issues tend to recur without a clear cause and may even occur during rest or sleep.

Tracking the frequency and timing of muscle cramps can help differentiate kidney-related symptoms from other causes. For instance, if cramps persist despite adequate hydration, stretching, and dietary adjustments, it may indicate an underlying medical problem. According to the National Kidney Foundation, recurring muscle cramps are a common symptom of chronic kidney disease due to the body’s inability to maintain proper electrolyte balance. If you notice a pattern of unexplained cramps, especially alongside other symptoms such as swelling or fatigue, it is important to discuss these findings with your healthcare provider for further evaluation and possible kidney function testing.

7. Loss of Appetite

Loss of appetite is a frequently overlooked symptom of kidney dysfunction, often mistaken for stress, digestive issues, or other medical conditions. As the kidneys lose their ability to effectively filter toxins and waste products from the blood, these substances start to accumulate and can negatively impact the gastrointestinal system. This buildup may lead to nausea, an unpleasant taste in the mouth, or a general sense of fullness, all of which reduce the desire to eat.

In real-world scenarios, individuals might notice they skip meals, feel full quickly, or lose interest in foods they previously enjoyed. These changes can develop gradually, making them easy to dismiss or attribute to lifestyle factors. However, persistent loss of appetite, especially when accompanied by other symptoms such as fatigue, changes in urination, or unexplained weight loss, warrants attention. The National Kidney Foundation highlights reduced appetite as a key sign of possible kidney disease. Keeping a food diary to monitor patterns in eating habits and sharing this information with a healthcare provider can aid in early detection and management. Prompt evaluation is crucial for preserving kidney function and overall health.

8. Nausea and Vomiting

Persistent nausea and vomiting can be a silent signal of kidney dysfunction, distinct from typical gastrointestinal ailments. As the kidneys fail to remove urea and other toxins effectively, these waste products accumulate in the body and can irritate the lining of the digestive tract. This irritation often leads to ongoing nausea, vomiting, or a continual unsettled feeling in the stomach that does not resolve with common remedies.

Unlike nausea related to food poisoning, viral infections, or indigestion, kidney-related symptoms tend to be chronic and may worsen over time as waste levels rise. These symptoms often occur alongside a metallic taste in the mouth or noticeable changes in appetite. The National Kidney Foundation notes that digestive complaints such as persistent nausea or vomiting, especially when paired with other unexplained symptoms like fatigue or swelling, should prompt further investigation for kidney disease. If you experience ongoing nausea without an obvious cause or relief, it is important to document the frequency and circumstances and to consult a healthcare provider for an evaluation. Early detection can help prevent further complications and improve quality of life.

9. Shortness of Breath

Shortness of breath is another subtle symptom that can be linked to impaired kidney function. When the kidneys are unable to remove excess fluid from the body, this fluid may accumulate in the lungs, making it difficult to breathe. Additionally, kidney disease can lead to anemia, a condition in which the body has fewer red blood cells to carry oxygen, resulting in feelings of breathlessness even with minimal exertion.

Unlike shortness of breath caused by respiratory illnesses such as asthma, chronic obstructive pulmonary disease (COPD), or infections, breathing difficulties related to kidney disease often lack associated symptoms like cough, wheezing, or chest congestion. Instead, they may gradually worsen over time and occur alongside other signs such as swelling in the ankles or general fatigue. The National Kidney Foundation advises that unexplained or persistent shortness of breath should not be ignored, especially if it is accompanied by other indicators of kidney dysfunction. Keeping a record of when and how often these episodes occur, and under what circumstances, can be valuable information for your healthcare provider in determining the cause and taking timely action.

10. High Blood Pressure

High blood pressure, or hypertension, is both a cause and a consequence of declining kidney function, creating a concerning cycle that often goes unnoticed in its early stages. The kidneys help regulate blood pressure by managing fluid balance and releasing hormones that control blood vessel constriction. When kidney function deteriorates, excess fluid and sodium can build up in the bloodstream, leading to elevated blood pressure. This increase in pressure can, in turn, further damage the delicate blood vessels within the kidneys, accelerating the progression of kidney disease.

Hypertension related to kidney dysfunction often develops gradually and may not present with any symptoms until it reaches a dangerous level. Many people only discover they have high blood pressure during routine checkups. Undetected or poorly managed hypertension can silently damage the kidneys and other organs over time. The American Kidney Fund stresses the importance of regular blood pressure monitoring, especially for individuals at risk of kidney disease. Using a home blood pressure monitor and tracking readings can help identify trends and signal when to seek medical advice. Early detection and management are crucial for protecting both kidney and cardiovascular health.

11. Metallic Taste in Mouth

A persistent metallic or ammonia-like taste in the mouth is a lesser-known but significant warning sign of kidney dysfunction. This symptom often arises due to a condition called uremia, in which waste products such as urea accumulate in the bloodstream and are eventually excreted into the saliva. The result is an altered sense of taste, with many individuals reporting that food tastes unusually metallic, bitter, or even foul.

Unlike temporary changes in taste caused by medications, dental issues, or upper respiratory infections, a metallic taste associated with kidney disease tends to linger and is frequently accompanied by other symptoms such as nausea, loss of appetite, or bad breath. The National Kidney Foundation notes that this sensory change, though subtle, can lead to decreased interest in eating and unintended weight loss. If you notice that familiar foods taste “off” or that you develop an ongoing metallic or chemical flavor in your mouth, especially alongside other symptoms of kidney trouble, it’s important to discuss these changes with your healthcare provider. Early recognition of uremia-related taste changes can support timely diagnosis and intervention for kidney disease.

12. Sleep Problems

Sleep disturbances, such as insomnia or restless nights, are common but often underestimated signs of kidney dysfunction. When the kidneys are not working efficiently, toxins and waste products build up in the bloodstream, which can interfere with normal sleep patterns. Many people with kidney issues report difficulty falling asleep, frequent nighttime awakenings, or even restless legs syndrome—a condition where uncomfortable sensations in the legs create an overwhelming urge to move them, especially at night.

Unlike sleep problems caused by stress, irregular routines, or excessive screen time, those linked to kidney disease may not improve with typical sleep hygiene practices. Instead, they often persist or worsen alongside other symptoms such as fatigue, itching, or changes in urination. The National Kidney Foundation highlights the strong connection between chronic kidney disease and sleep disturbances. If you experience ongoing sleep problems that do not respond to lifestyle changes or are accompanied by other unexplained symptoms, it’s important to consult a healthcare provider. Keeping a sleep diary can help track patterns and provide useful information for your doctor in identifying a potential link to kidney function.

13. Unusual Bruising

Unexplained or frequent bruising can be an overlooked symptom of kidney disease. Healthy kidneys help maintain proper blood composition, including the regulation of platelets and clotting factors. When kidney function declines, waste buildup and imbalances in blood components can disrupt normal blood clotting, making it easier for bruises to appear even after minor bumps or without any recognizable cause. These bruises may be larger, darker, or last longer than typical ones experienced during everyday activities.

Unlike bruising associated with medications like blood thinners or conditions such as vitamin deficiencies, bruising related to kidney disease often occurs in conjunction with other symptoms, including fatigue, swelling, or persistent infections. The National Kidney Foundation notes that bleeding and clotting issues are more common in advanced kidney disease. If you notice frequent or unexplained bruises, especially if they are accompanied by nosebleeds, bleeding gums, or other signs of abnormal bleeding, it is important to seek medical evaluation. Documenting the frequency, size, and location of bruises can provide valuable information for your healthcare provider and support earlier detection and management of potential kidney-related problems.

14. Foamy Urine

Foamy or bubbly urine can be an early sign of protein leakage due to kidney dysfunction. Normally, healthy kidneys prevent significant amounts of protein from entering the urine. When the filtering units of the kidneys (glomeruli) become damaged, proteins such as albumin may leak into the urine, creating a distinct foamy or frothy appearance. This is different from the small, short-lived bubbles that might occur after urinating quickly or from the force of the stream, which typically dissipate rapidly.

Persistent foaminess, especially if it occurs with every urination and does not subside, often suggests an abnormal amount of protein in the urine—a condition known as proteinuria. According to the National Kidney Foundation, proteinuria is a key marker for kidney disease and warrants prompt medical attention. If you notice that your urine consistently looks foamy or bubbly, particularly when combined with swelling in the hands, feet, or face, it is important to consult a healthcare provider. Keeping track of changes in your urine’s appearance and frequency can help your doctor identify underlying kidney problems and initiate appropriate testing and treatment early.

15. Back Pain or Side Pain

Pain in the lower back or sides can sometimes signal underlying kidney issues, particularly if it is persistent and not related to activity or injury. The kidneys are located on either side of the spine, just below the ribcage. When they become swollen due to infection, blockage, or inflammation, or when kidney stones are present, this can result in a dull ache or sharp pain known as flank pain. This discomfort may radiate from the back to the abdomen or groin and is often deeper and more constant than typical muscle aches.

It is important to distinguish kidney-related pain from musculoskeletal pain, which often worsens with movement or improves with rest and is associated with muscle tenderness. Kidney pain, on the other hand, may be accompanied by other symptoms such as fever, changes in urination, or nausea. The National Kidney Foundation emphasizes that persistent or severe pain in the lower back or sides—especially if paired with urinary symptoms—should not be ignored. If you experience this type of pain, seek medical evaluation to rule out kidney infection, stones, or other serious kidney conditions requiring prompt treatment.

16. Dark-Colored Urine

Dark-colored urine can be a significant but easily missed sign of kidney dysfunction. As the kidneys struggle to filter waste and excess fluid from the blood, urine may become concentrated and take on a deeper yellow, amber, or brown hue. While dehydration is a common cause of dark urine—since reduced water intake leads to more concentrated urine—persistent discoloration that does not improve with proper hydration can suggest an underlying problem with kidney function.

It’s important to distinguish this symptom from other causes of dark urine, such as liver disorders, which may also result in brownish urine due to increased bilirubin levels. Additionally, certain foods, medications, or supplements can temporarily alter urine color. According to the National Kidney Foundation, if you notice ongoing changes in your urine’s color, especially when accompanied by other symptoms like foamy urine, swelling, or fatigue, it’s a good idea to keep a log and discuss these observations with your healthcare provider. Tracking the frequency, duration, and any associated symptoms can help determine whether further testing for kidney disease or other medical conditions is necessary.

17. Bad Breath

Persistent bad breath—particularly a metallic or ammonia-like odor—can be a subtle sign of kidney dysfunction. When the kidneys are unable to efficiently filter waste products from the bloodstream, compounds such as urea build up and are broken down in the saliva, resulting in a distinctly unpleasant or chemical-smelling breath, medically referred to as “uremic fetor.” This type of bad breath is not typically resolved by brushing, mouthwash, or other oral hygiene measures.

Unlike halitosis caused by dental decay, gum disease, or poor oral hygiene, bad breath related to kidney issues often occurs alongside a metallic taste in the mouth, loss of appetite, or nausea. The National Kidney Foundation notes that this symptom may develop gradually and can be overlooked or attributed to dietary causes or infrequent brushing. If you or someone close to you notices persistent, unexplained bad breath—especially if it has an ammonia-like scent and is accompanied by other subtle signs of kidney problems—it is important to seek further evaluation. Early detection and diagnosis can improve outcomes and help prevent the progression of kidney disease.

18. Unexplained Weight Loss

Unintentional weight loss is a concerning symptom that may be linked to underlying kidney disease. As kidney function declines, the buildup of waste products and toxins in the body can lead to a variety of metabolic and gastrointestinal symptoms, including nausea, loss of appetite, and changes in taste. These factors can cause individuals to eat less, skip meals, or lose interest in previously enjoyed foods, resulting in gradual but persistent weight loss over time.

Unlike weight loss caused by intentional dieting, increased exercise, or temporary illnesses, the weight loss associated with kidney dysfunction is often subtle and may go unnoticed until clothing becomes loose or friends and family make comments. The National Kidney Foundation highlights unexplained weight loss as a common, yet underrecognized, warning sign of chronic kidney disease. It is important to monitor your weight regularly and note any gradual declines that are not explained by changes in activity or diet. If you observe ongoing weight loss—especially with symptoms like fatigue, swelling, or changes in urination—seek medical evaluation. Early detection can help address underlying kidney issues before they progress further.

19. Difficulty Thinking Clearly

Difficulty thinking clearly, sometimes described as “mental cloudiness” or confusion, is a symptom that can occur when kidney function declines. As the kidneys fail to adequately filter toxins from the bloodstream, these waste products can accumulate and disrupt normal brain function. This may lead to issues such as forgetfulness, poor concentration, disorganized thoughts, and trouble making decisions. These cognitive changes tend to occur gradually and are often mistaken for normal age-related memory problems or attributed to stress and lack of sleep.

Unlike mild forgetfulness that accompanies aging, the cognitive impairment associated with kidney disease may be more pronounced and persistent, affecting daily activities and work performance. According to the National Kidney Foundation, mental changes caused by kidney dysfunction may worsen if left unaddressed. To monitor cognitive health, consider keeping a diary of memory lapses, difficulties focusing, or confusion, and share this information with your healthcare provider. Engaging in regular mental exercises, maintaining a consistent routine, and asking loved ones to observe changes can also help identify cognitive decline early. Prompt evaluation and intervention may improve quality of life and slow further progression of kidney disease.

20. Itchy Eyes

Dry, itchy eyes can be a subtle sign of kidney dysfunction, although this symptom is often attributed to allergies, dry air, or extended screen use. When the kidneys are not able to maintain the body’s fluid and electrolyte balance, it can lead to dehydration and reduced tear production, resulting in dry and irritated eyes. Additionally, the buildup of waste products in the body may contribute to inflammation and itchiness around the eyes.

Unlike eye itchiness from allergies—which is often seasonal and accompanied by redness, watery discharge, or sneezing—itchy eyes related to kidney problems may persist regardless of the environment and may not respond to antihistamines or lubricating drops. According to the National Kidney Foundation, persistent dryness or itching of the eyes, especially when paired with other symptoms like swelling, fatigue, or changes in urination, should prompt further evaluation. To monitor this symptom, note the frequency, severity, and circumstances under which your eyes become itchy, and share this information with your healthcare provider. Early recognition and intervention can help manage underlying kidney issues and prevent complications.

21. Restless Legs

Restless legs syndrome (RLS) is a neurological disorder that causes an uncontrollable urge to move the legs, typically accompanied by uncomfortable sensations such as tingling, crawling, or itching. Kidney disease has been strongly linked to the development and worsening of RLS, primarily due to imbalances in iron, electrolytes, and the accumulation of waste products in the bloodstream. These factors can disrupt nerve function and contribute to the sensation of restlessness, particularly during periods of inactivity or at night.

In real-world scenarios, individuals with kidney-related restless legs often experience significant sleep disruption, as the urge to move the legs intensifies at bedtime, making it difficult to fall or stay asleep. This can lead to persistent fatigue, irritability, and decreased quality of life. According to the National Kidney Foundation, RLS is more prevalent in people with chronic kidney disease and can significantly impact overall well-being. If you notice persistent leg discomfort or an urge to move your legs that interferes with your sleep, it is important to track these symptoms and share them with your healthcare provider. Early recognition and management can improve sleep quality and daily functioning.

22. Persistent Hiccups

Persistent or recurring hiccups, though often regarded as harmless, can occasionally be a sign of underlying kidney dysfunction. The kidneys play a vital role in maintaining the body’s electrolyte balance, particularly levels of sodium, potassium, and calcium. When kidney function declines, imbalances in these electrolytes can irritate the diaphragm and its associated nerves, triggering episodes of prolonged or frequent hiccups that are difficult to resolve with common remedies like drinking water or holding your breath.

In contrast to hiccups caused by eating quickly, consuming carbonated beverages, or temporary stomach irritation, kidney-related hiccups may last for hours or even days and often recur without a clear trigger. According to a study referenced by the National Kidney Foundation, persistent hiccups can be a manifestation of advanced kidney disease or severe electrolyte disturbances. If you experience ongoing or unexplained hiccups, especially when accompanied by other symptoms such as nausea, fatigue, or changes in urination, it is important to seek medical evaluation. Early detection of electrolyte imbalances and kidney dysfunction can prevent complications and support timely intervention.

23. Easily Feeling Cold

Frequently feeling cold, even in warm environments, can be a subtle sign of kidney disease, often linked to anemia. Healthy kidneys produce erythropoietin, a hormone that prompts the body to make red blood cells. When kidney function declines, reduced erythropoietin leads to fewer red blood cells, resulting in anemia. With less oxygen being delivered to tissues, the body may react by feeling chilly or having cold hands and feet, despite normal surrounding temperatures.

This sensation of feeling cold differs from cold intolerance caused by thyroid disorders such as hypothyroidism, which generally includes symptoms like weight gain, hair loss, or constipation. In kidney-related anemia, the chilliness is often accompanied by fatigue, pale skin, or shortness of breath. The National Kidney Foundation notes that unexplained or persistent coldness should not be overlooked, especially if it occurs alongside other subtle symptoms of kidney disease. If you find yourself layering up more than usual or feeling cold without an obvious reason, it is important to track these sensations and consult your healthcare provider. Early evaluation can help identify anemia and underlying kidney dysfunction before they progress.

24. Pale Skin

Pale or sallow skin is another subtle sign that can indicate declining kidney function. Kidneys that are not working properly may produce less erythropoietin, a hormone necessary for the formation of red blood cells. This reduction leads to anemia, which in turn can cause noticeable pallor or a washed-out appearance of the skin and mucous membranes, such as the inside of the lips or eyelids. Sometimes, the skin may also take on a yellowish or grayish tint due to the buildup of waste products in the body.

Unlike temporary paleness caused by cold weather or brief illness, pallor linked to kidney disease is usually persistent and may be harder to detect, especially in those with darker skin tones. It’s helpful to check areas where the skin is normally lighter, such as the palms, nail beds, and the inside of the lower eyelid. The National Kidney Foundation advises that persistent or unexplained changes in skin tone, especially when accompanied by fatigue or weakness, should prompt medical evaluation. Noting changes over time and sharing photos with your healthcare provider can support early diagnosis and management of kidney-related anemia.

25. Chest Pain

Chest pain is a serious symptom that can sometimes be linked to kidney dysfunction, particularly when the condition has progressed. When the kidneys are unable to remove excess fluid from the body, fluid may accumulate around the heart (pericardial effusion) or in the lungs, leading to pressure, discomfort, or outright pain in the chest. Additionally, chronic kidney disease increases the risk of cardiovascular complications, including heart attacks and angina, due to the buildup of waste products and imbalances in electrolytes and blood pressure regulation.

Unlike chest discomfort caused by anxiety or heartburn, pain associated with kidney disease may be accompanied by shortness of breath, swelling in the legs, or palpitations. According to the National Kidney Foundation, any new, severe, or persistent chest pain warrants immediate medical attention, as it could signal a life-threatening emergency such as a heart attack or fluid overload. If chest discomfort is accompanied by other symptoms of kidney disease—such as fatigue, swelling, or changes in urination—do not delay seeking urgent care. Early intervention is essential for protecting both heart and kidney health and preventing dangerous complications.

26. Decreased Sexual Drive

Reduced sexual drive or libido is a frequently overlooked symptom that can be associated with kidney disease. As kidney function declines, the body’s balance of hormones—including those involved in sexual health—can be significantly disrupted. For men, this may result in lower testosterone levels, while women might experience irregular menstrual cycles or changes in estrogen production. Additionally, fatigue, anemia, and the buildup of waste products can all contribute to a general decline in energy and interest in sexual activity.

Unlike low libido caused by psychological factors such as stress, relationship issues, or depression, sexual dysfunction linked to kidney disease is often persistent and may be accompanied by other symptoms, such as fatigue, muscle cramps, or sleep disturbances. According to the National Kidney Foundation, changes in sexual desire and function are common in people with chronic kidney disease and may signal hormonal or vascular problems. If you notice a decrease in sexual interest that does not improve with lifestyle changes or counseling, it is important to discuss this with your healthcare provider. Early recognition can help address underlying kidney issues and improve quality of life and relationships.

27. Difficulty Breathing When Lying Down

Difficulty breathing when lying down, known as orthopnea, is a symptom that can be associated with advanced kidney disease. When the kidneys are unable to efficiently eliminate excess fluid from the body, this fluid can accumulate in the lungs, making it harder to breathe—especially when in a horizontal position. People may notice that they need to prop themselves up with extra pillows or sleep partially upright to relieve the sensation of breathlessness at night.

This symptom closely overlaps with heart disease, as both conditions can cause fluid buildup in the lungs and similar respiratory discomfort. However, in kidney disease, orthopnea is often accompanied by other signs such as swelling in the ankles, changes in urination, and unexplained fatigue. According to the National Kidney Foundation, difficulty breathing when reclining should always be taken seriously, as it could indicate a dangerous degree of fluid overload or concurrent heart issues. If you experience this symptom, particularly if it is new or worsening, it is essential to seek prompt medical evaluation. Early intervention can help manage fluid balance and prevent serious complications involving both the kidneys and the heart.

28. Frequent Nighttime Urination

Frequent nighttime urination, known medically as nocturia, can be an early sign of kidney impairment. As the kidneys lose their ability to concentrate urine and properly regulate fluid balance, more urine is produced, particularly at night. This leads to repeated awakenings to use the bathroom, which can disrupt sleep and contribute to daytime fatigue. While occasional nighttime urination is normal, especially as people age, a noticeable increase in frequency may warrant further investigation.

Nocturia can also occur due to other factors such as diabetes, prostate issues in men, or simply increased fluid intake before bed. However, when associated with kidney disease, it is often accompanied by other symptoms such as swelling, persistent fatigue, or changes in urine appearance. The National Kidney Foundation emphasizes the importance of monitoring urinary patterns, as a sudden or gradual increase in nighttime urination can be a subtle but significant warning sign. If you find yourself regularly waking to urinate more than once per night without an obvious reason, it is important to track this symptom and discuss it with your healthcare provider. Early detection can support timely intervention and protect kidney function.

29. Difficulty Catching Breath After Exertion

Struggling to catch your breath after physical activity can be a subtle sign of kidney dysfunction, often linked to anemia or fluid overload. As kidney disease progresses, the body’s production of erythropoietin—a hormone essential for red blood cell formation—declines, resulting in fewer red blood cells to transport oxygen. This anemia means that even mild exertion, such as climbing stairs or walking briskly, can leave you unusually winded and slow to recover.

Alternatively, impaired kidneys may cause fluid to build up in the lungs, further reducing oxygen exchange and making post-exertion breathlessness more pronounced. While shortness of breath after strenuous exercise is normal, persistent or disproportionate difficulty catching your breath following routine activities may indicate an underlying issue. According to the National Kidney Foundation, monitoring your endurance and noting any changes in how quickly you recover from exertion can provide valuable clues. Keep a log of your activities, the duration and intensity, and how long it takes to return to normal breathing. If you notice a decline in your exercise tolerance without a clear cause, consult your healthcare provider for further evaluation of your kidney and cardiovascular health.

30. Swollen Face or Eyes in the Morning

Waking up with a puffy face or swollen eyes can be an early, subtle sign of kidney dysfunction. When the kidneys are not filtering waste and excess fluid efficiently, fluid tends to accumulate in the soft tissues overnight, resulting in noticeable facial swelling, particularly around the eyes. This edema is often more pronounced in the morning and may subside as the day progresses and gravity redistributes the fluid throughout the body.

Unlike puffiness caused by allergies, which is usually accompanied by redness, itching, or watery eyes, kidney-related swelling is typically painless and persistent. Real-life examples include individuals noticing that their eyelids are unusually puffy upon waking or requiring extra time for facial swelling to diminish. According to the National Kidney Foundation, facial edema is a classic but frequently overlooked symptom of early kidney disease. To monitor this sign, take note of any morning facial puffiness, how long it lasts, and whether it is accompanied by swelling in other areas like the ankles or hands. If swelling becomes a regular occurrence, it is important to consult a healthcare provider for kidney function assessment.

31. Rashes or Skin Discoloration

Rashes or changes in skin color can be a subtle but telling sign of kidney dysfunction. When the kidneys fail to remove toxins and waste products from the body, these substances can accumulate and cause irritation, leading to dryness, redness, or bumpy rashes. Some individuals may notice darkening of the skin, yellowish or ashy patches, or an overall change in skin tone. These changes often do not respond to typical treatments for eczema or dermatitis and may be accompanied by persistent itching.

Unlike common rashes caused by allergies, infections, or contact with irritants, kidney-related skin changes tend to develop gradually and may occur alongside other signs of kidney problems, such as swelling, fatigue, or changes in urination. The National Kidney Foundation highlights that chronic kidney disease can cause both pruritus and various pigment changes due to toxin buildup and alterations in mineral balance. If you experience unexplained or persistent skin rashes or discoloration, especially in conjunction with other symptoms, it is important to consult your healthcare provider. Documenting the appearance, duration, and triggers of skin changes can assist in early diagnosis and management of kidney-related complications.

32. Mild Fever Without Obvious Cause

A mild, persistent fever without a clear source can be a subtle indicator of a kidney infection or underlying kidney inflammation. Unlike high fevers associated with acute viral or bacterial illnesses, kidney-related fevers often remain low-grade—typically between 99°F and 101°F (37.2°C to 38.3°C)—and may be accompanied by vague symptoms such as fatigue, back pain, or changes in urination. These fevers can linger for days or weeks, making them easy to overlook or attribute to minor viral infections or stress.

While most fevers from common colds or flu are accompanied by respiratory symptoms like cough, congestion, or sore throat, a mild fever due to kidney issues may occur without these classic signs. According to the National Kidney Foundation, kidney infections (pyelonephritis) can start subtly and escalate if left untreated. To monitor for this symptom, regularly check your temperature when feeling unwell and keep a log of any recurring low-grade fevers, noting their duration and any associated symptoms. If a mild fever persists without a clear explanation or is accompanied by other kidney-related signs, seek prompt medical evaluation to prevent complications.

33. Decreased Urine Output

One of the more alarming signs of kidney dysfunction is a noticeable decrease in urine output, a condition known as oliguria. When the kidneys lose their ability to filter blood and regulate fluid balance, they may produce far less urine than normal. This decrease can happen gradually or suddenly, and often results in less frequent trips to the bathroom, smaller amounts of urine, or sometimes a near-complete stop in urination.

It is important to differentiate decreased urine output caused by kidney failure from that caused by dehydration. Dehydration, which can result from vomiting, diarrhea, or insufficient fluid intake, typically resolves when hydration is restored. In contrast, decreased urine due to kidney dysfunction will not improve with increased fluid intake and may be accompanied by other symptoms, such as swelling, fatigue, or changes in urine color. According to the National Kidney Foundation, persistent reduction in urine output is a red flag for acute or chronic kidney injury and warrants immediate medical attention. If you notice a marked decrease in urination that does not resolve with adequate hydration, seek prompt evaluation to prevent serious complications.

34. Persistent Headaches

Chronic or persistent headaches can be an underrecognized sign of kidney dysfunction. Two common factors contribute to headaches in people with kidney disease: high blood pressure (hypertension) and the accumulation of toxins in the bloodstream. As the kidneys lose their ability to regulate blood pressure, hypertension can develop or worsen, often presenting as throbbing or pressure-like headaches. Additionally, the buildup of waste products that the kidneys fail to filter out may directly irritate the nervous system, leading to frequent headaches or migraines.

Unlike headaches triggered by dehydration, eye strain, or sinus issues, those linked to kidney disease are often more persistent and may occur alongside other symptoms such as fatigue, dizziness, or visual disturbances. The National Kidney Foundation notes the importance of monitoring headache patterns, especially if they are new, worsening, or resistant to typical treatments. Keeping a headache diary—including frequency, intensity, duration, and any accompanying symptoms—can provide valuable information for your healthcare provider. If you experience ongoing headaches in combination with high blood pressure or other signs of kidney dysfunction, prompt medical evaluation is recommended to address underlying causes and protect your health.

35. Persistent Heartburn

Persistent heartburn or acid reflux can be an overlooked consequence of declining kidney function. As waste products build up in the bloodstream due to impaired kidney filtration, they can disrupt normal digestive processes and increase the production of stomach acid. This accumulation of toxins may irritate the lining of the gastrointestinal tract, leading to symptoms such as frequent heartburn, indigestion, or a burning sensation in the chest and throat. In some cases, these symptoms persist despite the use of over-the-counter antacids or dietary adjustments.

Unlike occasional heartburn triggered by spicy foods, overeating, or stress, kidney-related heartburn tends to be more chronic and may be accompanied by nausea, loss of appetite, or changes in taste. According to the National Kidney Foundation, gastrointestinal symptoms like persistent heartburn should not be ignored, especially if they are associated with other signs of kidney dysfunction. If you find yourself experiencing ongoing reflux despite lifestyle changes, keep a log of your symptoms, triggers, and any patterns that emerge. Discuss these findings with your healthcare provider, as managing the underlying kidney issue is essential for relieving digestive discomfort and preventing further complications.

36. Numbness or Tingling in Extremities

Numbness or tingling in the hands, feet, or other extremities can be a subtle but significant sign of kidney dysfunction. As the kidneys lose their ability to filter toxins and maintain proper electrolyte balance, waste products accumulate in the bloodstream, which can damage peripheral nerves. This condition, known as uremic neuropathy, often manifests as unusual sensations such as pins and needles, burning, or loss of feeling in the fingers and toes.

While diabetic neuropathy is a well-known cause of similar symptoms—resulting from high blood sugar damaging nerves—neuropathy associated with kidney disease is specifically related to toxin buildup and electrolyte imbalances. According to the National Kidney Foundation, these sensory changes can develop gradually and may be accompanied by muscle weakness, cramping, or difficulty with coordination. If you notice persistent numbness, tingling, or unusual sensations that do not resolve with changes in posture or activity, it is important to document the frequency, location, and severity of symptoms. Discuss these findings with your healthcare provider to determine whether kidney function testing or further neurological evaluation is warranted, as early intervention can help prevent permanent nerve damage.

37. Frequent Nosebleeds

Frequent or unexplained nosebleeds can be a subtle symptom of compromised kidney function. Healthy kidneys help regulate blood clotting by maintaining the balance of platelets and clotting factors in the blood. When kidney function declines, this balance is disrupted, leading to a higher risk of bleeding—even from minor blood vessel injuries, such as those in the delicate lining of the nose. This can result in frequent or prolonged nosebleeds, which may occur spontaneously or with minimal irritation.

It’s important to distinguish kidney-related nosebleeds from those caused by environmental factors like dry air, allergies, or nose picking, which usually have clear triggers or are seasonal. Nosebleeds linked to kidney dysfunction may be more persistent, occur without an obvious reason, or be accompanied by other symptoms such as bruising, gum bleeding, or fatigue. According to the National Kidney Foundation, increased bleeding or clotting problems should not be ignored, especially in the context of other warning signs. If you experience frequent nosebleeds, keep a record of their frequency and duration, and consult your healthcare provider for further testing to rule out kidney-related clotting abnormalities.

38. Difficulty Regulating Blood Sugar

Difficulty maintaining stable blood sugar levels can be an underappreciated consequence of kidney impairment. The kidneys play a vital role in metabolizing insulin and removing excess glucose from the bloodstream. When kidney function declines, insulin and glucose metabolism become less efficient, leading to unpredictable fluctuations in blood sugar. This can be particularly problematic for people with diabetes, but it may also affect those without a prior diagnosis, causing symptoms such as fatigue, confusion, or unexplained changes in energy.

Unlike blood sugar instability caused by dietary indiscretions or acute illness, glucose regulation issues related to kidney disease tend to be persistent and may not respond well to routine adjustments in medication or meal planning. According to the American Kidney Fund, those with chronic kidney disease are at increased risk for both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Regular monitoring of blood glucose levels, even for individuals without diabetes, can provide early clues to kidney involvement. If you notice frequent, unexplained swings in blood sugar, discuss these changes with your healthcare provider, as timely intervention can help protect both kidney and metabolic health.

39. Persistent Metallic or Ammonia Odor in Sweat

A persistent metallic or ammonia-like odor in sweat can be an unusual but telling sign of kidney dysfunction. As the kidneys lose their ability to filter waste products efficiently, substances such as urea accumulate in the bloodstream. The body attempts to eliminate these toxins through other means, including the skin, which can result in sweat that smells distinctly metallic or similar to ammonia. This odor is often more noticeable after physical activity or in warm weather, when sweat production increases.

Unlike temporary body odor changes caused by diet, stress, or poor hygiene, the scent associated with kidney issues tends to linger despite regular washing and is resistant to antiperspirants or deodorants. Real-world examples include individuals or their close contacts noticing an unusual chemical or “cat urine” type smell on clothes or bedding. According to the National Kidney Foundation, persistent changes in body odor—especially when accompanied by other symptoms like fatigue, appetite loss, or changes in urination—should prompt further medical evaluation. If you or those around you notice a consistent, unexplained metallic or ammonia odor, consult your healthcare provider for kidney function testing and assessment.

40. Trouble Swallowing

Trouble swallowing, or dysphagia, can occasionally be connected to kidney disease due to the impact of toxin accumulation and electrolyte imbalances on nerve and muscle function. When the kidneys are not filtering waste properly, the buildup of toxins can disrupt the normal operation of the nerves and muscles involved in swallowing. This may result in sensations of food sticking in the throat, difficulty starting a swallow, or even coughing and choking during meals.

Unlike temporary swallowing problems from throat infections, such as strep throat or tonsillitis—which are typically accompanied by pain, redness, and fever—kidney-related dysphagia is often painless and more persistent. It may also be accompanied by other symptoms of kidney dysfunction, including muscle cramps, numbness, or changes in taste. According to the National Kidney Foundation, nerve and muscle complications are more common in advanced kidney disease and should not be ignored. If you experience ongoing difficulty swallowing, keep track of when it occurs, its severity, and any associated symptoms. Share this information with your healthcare provider for further evaluation and to prevent complications such as malnutrition or aspiration.

41. Metallic Odor in Breath or Sweat

A metallic odor in the breath or sweat is a distinctive and sometimes overlooked sign of kidney dysfunction. As kidney function declines, waste products such as urea accumulate in the blood. These uremic toxins are partially excreted through the lungs and sweat glands, imparting a metallic, ammonia-like, or even fishy smell to both breath and perspiration. This phenomenon, known as “uremic fetor,” is particularly noticeable to close contacts and can persist regardless of oral hygiene or the use of deodorants.

Examples include individuals noticing a persistent metallic taste in their mouth or family members commenting on an unusual odor after exercise or during periods of heavy sweating. Unlike transient odors caused by certain foods, medications, or poor dental care, metallic scents linked to kidney issues are chronic and often accompanied by other symptoms such as fatigue, loss of appetite, or changes in urination. The National Kidney Foundation stresses the importance of noting these subtle changes. To monitor, keep track of how often you or others notice the metallic odor and whether it correlates with other warning signs. Consistent findings should prompt a discussion with your healthcare provider and consideration of kidney function testing.

42. Decreased Alertness

Decreased alertness or mental sluggishness can be an early and subtle indication of kidney dysfunction. As the kidneys lose their ability to filter toxins from the bloodstream, waste products accumulate and interfere with normal brain function. This cognitive slowing may manifest as difficulty focusing, slower response times, forgetfulness, or a general sense of being mentally “foggy.” Unlike temporary fatigue caused by a poor night’s sleep or a busy day, decreased alertness linked to kidney problems tends to persist and may slowly worsen over time.

It can be challenging to distinguish this symptom from everyday tiredness or the effects of stress. However, if you or those around you notice consistent problems with attention, memory, or reaction speed—especially when these issues do not resolve with rest or changes in routine—they may warrant further investigation. According to the National Kidney Foundation, cognitive symptoms such as decreased alertness are common even in early stages of chronic kidney disease. Keeping a journal of mental lapses, slow thinking, or changes in alertness can be helpful for discussing these patterns with your healthcare provider, who may recommend kidney function testing if other warning signs are present.

43. Slow Healing of Cuts or Wounds

Slow healing of cuts, scrapes, or wounds can be a subtle sign of underlying kidney dysfunction. Healthy kidneys help regulate essential functions such as blood flow, immune response, and the balance of nutrients necessary for tissue repair. When kidney function declines, waste products accumulate, circulation may be impaired, and the body’s natural healing processes can be slowed. This can result in wounds that remain open, take longer than expected to close, or are more prone to infection.

While slow wound healing is commonly associated with diabetes due to poor blood sugar control and nerve damage, kidney disease can independently contribute to this problem—even in people without diabetes. According to the National Kidney Foundation, chronic kidney disease can compromise not only blood flow but also the immune system, making it harder for the body to fight off bacteria and repair tissue damage. To aid healing, keep wounds clean, avoid unnecessary pressure, and report any signs of delayed healing, redness, swelling, or persistent pain to your healthcare provider. Early intervention can prevent complications and support both wound recovery and overall kidney health.

44. Intolerance to Exercise

Intolerance to exercise, or a marked decrease in stamina, can be a subtle but telling symptom of kidney dysfunction. When the kidneys are not functioning properly, they may produce less erythropoietin, a hormone that stimulates the production of red blood cells. This leads to anemia, reducing the blood’s ability to carry oxygen to muscles during physical activity. As a result, even mild exercise may leave you feeling unusually tired, short of breath, or weak.

Fluid overload, another consequence of impaired kidney function, can further limit exercise tolerance. Excess fluid can accumulate in the lungs and tissues, making it even harder to breathe and causing discomfort with exertion. Unlike the gradual decline in stamina that occurs with aging or lack of physical activity, exercise intolerance from kidney disease tends to develop more rapidly and may be accompanied by other symptoms such as swelling, fatigue, or muscle cramps. The National Kidney Foundation recommends paying close attention to changes in your ability to perform routine activities. If you notice a sudden or persistent drop in your stamina, or difficulty recovering after exercise, consult your healthcare provider for assessment and possible kidney function testing.

45. Persistent Dry Mouth

Persistent dry mouth, or xerostomia, is a symptom that may arise from kidney dysfunction, often due to dehydration or altered fluid balance. When the kidneys are unable to retain or eliminate fluid properly, this can result in either fluid overload or, paradoxically, dehydration—especially if excessive urination or vomiting is present. The reduction in saliva production can cause a constant feeling of dryness, increased thirst, difficulty swallowing, and even changes in taste.

Unlike temporary dry mouth caused by medications, anxiety, or short-term dehydration, kidney-related xerostomia tends to be ongoing and may not improve with increased fluid intake alone. Individuals might notice they frequently need to sip water, wake at night to drink, or experience a sticky or burning sensation in the mouth. According to the National Kidney Foundation, persistent dry mouth is a common but often overlooked symptom of chronic kidney disease. To help manage this symptom, try sipping water regularly, avoiding caffeine and alcohol, and using a humidifier at night. If dry mouth persists despite these measures, it is important to consult your healthcare provider to rule out kidney and other underlying health issues.

46. Easy Sunburn or Sensitivity

Increased sensitivity to sunlight and a tendency to burn easily can be subtle signs of underlying kidney disease. As kidney function declines, the skin may undergo changes due to the accumulation of waste products, alterations in mineral balance, and reduced ability to repair itself. These changes can result in thinner, more fragile skin that is less able to protect against ultraviolet (UV) rays, making even brief sun exposure more likely to cause sunburn or irritation.

This heightened sun sensitivity is distinct from typical burning caused by prolonged exposure or lack of sunscreen. Individuals with kidney dysfunction may notice redness, itching, or rashes on areas exposed to sunlight, even after short periods outdoors. According to the National Kidney Foundation, chronic kidney disease can increase the risk of various skin problems, including photosensitivity. To monitor, be aware of any changes in your skin’s response to sunlight and note if you develop sunburn more quickly than usual. Wearing protective clothing, using broad-spectrum sunscreen, and limiting direct sun exposure are practical measures. If you experience persistent or severe sun sensitivity, consult your healthcare provider for further evaluation and support.

47. Unexplained Anxiety or Mood Changes

Unexplained anxiety or sudden mood changes can be subtle but impactful signs of kidney dysfunction. As the kidneys lose their ability to filter waste and maintain proper chemical balance in the blood, toxins and electrolyte imbalances can affect the nervous system and brain. This disruption may lead to heightened feelings of anxiety, irritability, depression, or emotional instability, even in individuals with no prior history of mental health concerns.

Unlike mood shifts caused by external stressors, major life events, or psychiatric conditions, those linked to kidney disease often appear without a clear trigger and can fluctuate with other symptoms such as fatigue, trouble concentrating, or changes in sleep patterns. According to the National Kidney Foundation, psychological changes are common in people with chronic kidney disease and may worsen as kidney function declines. To monitor mental health, keep a journal of mood changes, anxiety episodes, or persistent sadness, and note any correlations with physical symptoms. If you experience ongoing emotional difficulties or behavioral changes that interfere with daily life, it’s important to share this information with your healthcare provider for a comprehensive evaluation.

48. Persistent Cough

A persistent, unexplained cough can be a warning sign of kidney dysfunction, especially when caused by fluid overload. When the kidneys are unable to remove excess fluid efficiently, it can accumulate in the lungs, leading to irritation and a chronic cough. This cough is often described as dry or sometimes producing frothy sputum, and may worsen when lying down, disrupting sleep or daily activities.

Unlike coughs caused by respiratory infections, asthma, or chronic obstructive pulmonary disease (COPD)—which are typically accompanied by fever, wheezing, or chest tightness—a cough linked to kidney issues is more often associated with other symptoms of fluid retention, such as swelling in the ankles, shortness of breath, or rapid weight gain. According to the National Kidney Foundation, chronic cough in the absence of common lung diseases should prompt consideration of cardiac or renal causes. If you notice a persistent cough that does not improve with typical treatments or is accompanied by other signs of kidney dysfunction, it’s important to seek medical evaluation. Early diagnosis and management can prevent complications and improve both lung and kidney health.

49. Unsteady Gait or Balance Issues

Unsteady gait or balance issues can arise as a result of nerve and muscle impairment caused by advancing kidney disease. When the kidneys are unable to efficiently filter waste and maintain electrolyte balance, toxins build up in the body and can damage peripheral nerves (uremic neuropathy) or weaken muscles. This may manifest as difficulty walking, frequent stumbling, feeling wobbly, or an increased risk of falls, especially in older adults.

Unlike balance problems caused by inner ear disorders, low blood pressure, or certain neurological diseases, kidney-related unsteadiness often occurs alongside other symptoms such as numbness, tingling in the extremities, or muscle cramps. According to the National Kidney Foundation, chronic kidney disease can interfere with both nerve and muscle function, increasing the risk of mobility challenges. To monitor, keep track of any new or worsening difficulty walking, unexplained falls, or hesitation when changing direction. If you or someone you care for experiences persistent balance issues, it’s important to report these symptoms to a healthcare provider. Early intervention can help prevent injuries and support safer mobility while addressing the underlying kidney problem.

50. Subtle Vision Changes

Subtle changes in vision can be an overlooked symptom of kidney dysfunction, often linked to high blood pressure or the accumulation of toxins in the bloodstream. When kidneys fail to regulate blood pressure effectively, persistent hypertension can damage the delicate blood vessels in the eyes (retinopathy), resulting in blurred vision, difficulty focusing, or seeing spots. Additionally, buildup of waste products may affect the nerves responsible for vision, leading to gradual or intermittent changes in eyesight.

Unlike sudden vision loss from trauma or acute eye infections, kidney-related vision changes tend to develop slowly and may fluctuate with blood pressure or fluid levels. According to the National Kidney Foundation, individuals with chronic kidney disease should be vigilant for signs such as increased difficulty reading, trouble adjusting to low light, or frequent changes in eyeglass prescriptions. To monitor, regularly check your ability to read small print, notice street signs, or distinguish colors. If you experience gradual vision changes—especially alongside other kidney-related symptoms—report them promptly to your healthcare provider. Early detection and management can help preserve both eye health and kidney function.

Conclusion

Recognizing the silent and often overlooked symptoms of kidney dysfunction is crucial for early intervention and better health outcomes. Many of these subtle signs can be mistaken for other conditions or dismissed as minor issues. If you notice any of these persistent symptoms—especially if you have risk factors like diabetes or high blood pressure—timely action is essential. Schedule regular checkups and request kidney function tests, such as blood and urine analyses. The National Kidney Foundation recommends annual screenings for those at risk. Early detection and management can slow disease progression and help maintain overall well-being.

Disclaimer

The information provided in this article is for general informational purposes only. While we strive to keep the information up-to-date and correct, we make no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability, or availability with respect to the article or the information, products, services, or related graphics contained in the article for any purpose. Any reliance you place on such information is therefore strictly at your own risk.

In no event will we be liable for any loss or damage including without limitation, indirect or consequential loss or damage, or any loss or damage whatsoever arising from loss of data or profits arising out of, or in connection with, the use of this article.

Through this article you are able to link to other websites which are not under our control. We have no control over the nature, content, and availability of those sites. The inclusion of any links does not necessarily imply a recommendation or endorse the views expressed within them.

Every effort is made to keep the article up and running smoothly. However, we take no responsibility for, and will not be liable for, the article being temporarily unavailable due to technical issues beyond our control.