
The Upcoming Cure to Treat Cancer
Hyperactive pediatric tumors are complex to treat because of the toxicity associated with chemotherapy. However, some scientists are working with developing effective treatments that do not have harmful side effects. Researchers at Standford worked on a study around a rather new molecule called CD47, a protein expressed on the cell’s surface and how the molecule interacts with the macrophages, white blood cells that eliminate the abnormal cells. The lead study author and assistant professor of neurosurgery at the university said that the macrophages were considered similar to the Pac-Man.
CD47 transfers the macrophages a “do not harm me” signals, and the cancer cells trick the immune system into not destroy them by producing a high amount of CD47. When the researchers blocked the messages on the cancer cells, the macrophages identified the cancer cells and killed them without any toxic side effects. This treatment successful shrank five of the most common pediatric tumors without the harmful implications of chemotherapy.