The Weirdest Diseases We Hope You Never Have To Live Through

The Disease That Makes You Hear Explosions As You Fall Asleep

People with Exploding Head Syndrome claim to hear extremely loud sounds, like gunshots or marching band drums, as they fall asleep or wake up when no real sounds are happening around them. The noise can be frightening, but it is not a serious health concern. Around 10% of people with EHS also have visual disturbances like seeing static, lightning, or flashes of light. Others experience heat or electric tinglings that ascend to the head before the auditory hallucinations occur. The patterns vary, with some reporting they have a total of 2-4 attacks and then never experience it again. Still, others have attacked for a lifetime over days, weeks, or months. The cause of EHS is unknown. However, researchers theorize that it links to the part of our brain responsible for transitioning between wake and sleep. There is much room for research to be done on this disease. Many doctors believe most patients never seek medical treatment for the condition, so it goes unrecognized.

The Disease That Makes Your Hands And Feet Feel Like They’re Burning

Fabry disease is a rare genetic disorder caused by a deficiency of the alpha-galactosidase A enzyme, leading to the buildup of a fatty substance called Gb3 in the body’s cells. This buildup can cause a variety of symptoms, such as pain and burning sensations in the hands and feet, skin rashes and lesions, gastrointestinal issues, eye abnormalities, kidney dysfunction, and heart problems. The disease is primarily inherited in an X-linked pattern and affects males more than females, with symptoms typically appearing in childhood or adolescence and progressing over time. Treatment may include enzyme replacement therapy and other supportive measures to manage symptoms and prevent complications.

The Disease That Prevents You From Feeling Physical Pain

Congenital analgesia is a rare condition in which a person is born without the ability to feel physical pain. This can be caused by genetic mutations that affect the functioning of the nervous system, including the pathways responsible for processing pain signals. People with congenital analgesia are unable to perceive any type of physical pain, including pain caused by injury, inflammation, or illness. While this may sound like a desirable condition, it can actually be quite dangerous, as the ability to feel pain is an important protective mechanism that helps prevent injury and illness. People with congenital analgesia are at risk of sustaining injuries or developing illnesses that they may not be aware of, as they do not experience the pain that would normally alert them to seek medical attention. As a result, they may have a shorter lifespan and a higher risk of complications from injuries and illnesses.

Where Do We Find This Stuff? Here Are Our Sources:

verywellhealth.com/fatal-familial-insomnia-overview-4588665