Life-Saving Medical Discoveries That Happened On Accident

Anti-Tumor Necrosis Factor (TNF) Therapy

In the 1990s, researchers discovered the anti-TNF properties of infliximab, a monoclonal antibody originally developed for other purposes. This unexpected finding led to further investigations and the development of anti-TNF therapies, which work by targeting and inhibiting TNF, a protein involved in the inflammatory response. These therapies, including drugs such as infliximab, adalimumab, and etanercept, have proven highly effective in managing conditions such as rheumatoid arthritis, psoriasis, and Crohn’s disease. By blocking TNF, these medications reduce inflammation, alleviate symptoms, and improve the quality of life for patients with autoimmune diseases.

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