Biologic agents are drugs that work by targeting specific molecules in the immune system that contribute to psoriasis symptoms. These medications are administered by injection or infusion and are designed to be more targeted and less toxic than traditional systemic medications. Biologics can also improve patients’ quality of life by reducing pain, itching, and social embarrassment that is sometimes associated with psoriasis. While biologic agents are generally considered safe, they can have potential side effects. These include an increased risk of infection, reactions at the injection site, and the development of certain types of cancers. A few of the biologic medications available are Cimzia, Enbrel, Humira, and Remicade.